A database of hormones and their receptors
Non-peptide Hormone

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HMRbase accession number1113
PubChem ID6013
Hormone nameTestosterone
DescriptionA potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
SynonymsTestosterone Testosteron Androderm Oreton Methyltestosterone Mertestate Testoderm Androlin trans-Testosterone Testex
Molecular weight288.42
Molecular formulaC19H28O2
IUPAC Name(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Canonical smilesCC12CCC3C(C1CCC2O)CCC4=CC(=O)CCC34C
Isomeric smilesC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=CC(=O)CC[C@]34C
Structure
   
PDB file
SDF file
MOL file
PDB ID1I37  1I38  1I9J  1J96  1Q13  1VPO  2Q7I  2Q7J  2Q7K  2Q7L  1AFS  
KEGG IDC00535  D00075  
HMDB IDHMDB00234
Melting Point155(EXP)
Log P3.32(EXP)
Water Solubility23.4(EXP) at 25C
DrugBank IDDB00624
Drugpediawiki
ReceptorP10275   Detail in HMRbase   
Comments
ReferencesPubchem,HMDB