HMRbase accession number | 11046 |
Swiss-prot Accession number | P21752 (Sequence in FASTA format) |
Description | Thymosin beta-10 (Thymosin beta-9) [Contains: Thymosin beta-8]. |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Cytoplasm |
Developmental Stage | N/A |
Similarity | Belongs to the thymosin beta family. |
Tissue Specificity | Distributed in numerous types of tissues, including thymus, spleen, lung, liver and muscle |
Post translational modification | N/A |
Function | Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization |
Protein Length | 42 Amino acids |
Molecular weight | 4805 |
References | 1 Gutierrez-Pabello J.A., Adams L.G.; "Bovine thymosin beta-10 full length cDNA sequence."; Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 6952223 3 PubMed abstract 3818171 4 Gallert B., Zarbock J., Voelter W., Holak T.A.; "A nuclear magnetic resonance and simulated annealing study ofthymosin beta-9 in solution."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.517-518, Escom Science Publishers, Leiden (1993).
5 PubMed abstract 9108730
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Domain Name | Thymosin |
Hormone Name | Thymosin beta-8 |
Mature Hormone Sequence | ADKPDLGEINSFDKAKLKKTETQEKNTLPTKETIEQEKQ |
Position of mature hormone in Pre-Hormone protein | 39 Residues from position (2-40) |
Receptor | N/A |
Gene ID | 282385 |
PDB ID | 1HJ0 |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |