A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number11045
Swiss-prot Accession numberP21752 (Sequence in FASTA format)
DescriptionThymosin beta-10 (Thymosin beta-9) [Contains: Thymosin beta-8].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityDistributed in numerous types of tissues, including thymus, spleen, lung, liver and muscle
Post translational modificationN/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length42 Amino acids
Molecular weight4805
References1   Gutierrez-Pabello J.A., Adams L.G.; "Bovine thymosin beta-10 full length cDNA sequence."; Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 6952223
3  PubMed abstract 3818171
4   Gallert B., Zarbock J., Voelter W., Holak T.A.; "A nuclear magnetic resonance and simulated annealing study ofthymosin beta-9 in solution."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.517-518, Escom Science Publishers, Leiden (1993).
5  PubMed abstract 9108730
Domain NameThymosin  
Hormone NameThymosin beta-10
Mature Hormone SequenceADKPDLGEINSFDKAKLKKTETQEKNTLPTKETIEQEKQAK
Position of mature hormone in Pre-Hormone protein41 Residues from position (2-42)
ReceptorN/A
Gene ID282385      
PDB ID1HJ0      
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated