A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 11040 |
| Swiss-prot Accession number | P06454 (Sequence in FASTA format) |
| Description | Prothymosin alpha [Contains: Thymosin alpha-1]. |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the pro/parathymosin family. |
| Tissue Specificity | N/A |
| Post translational modification | Covalently linked to a small RNA of about 20 nucleotides (By similarity). |
| Function | Thymosin alpha1 (Talpha1) is an oligopeptide hormone originally isolated from the thymus gland, and has been reported to have stimulating effects on the differentiation of T cells and NK cells |
| Protein Length | 111 Amino acids |
| Molecular weight | 12203 |
| References | 1 PubMed abstract 3467312 2 PubMed abstract 3466166 3 PubMed abstract 2708378 4 PubMed abstract 2785990 5 Li Z., Fan Q., Huang W., An L.; "A novel prothymosin alpha cDNA from thymus."; Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases. 6 PubMed abstract 15489334 7 PubMed abstract 7916742 8 PubMed abstract 3532956 9 PubMed abstract 8485135 10 PubMed abstract 17081983 |
| Domain Name | Prothymosin |
| Hormone Name | Thymosin alpha-1 |
| Mature Hormone Sequence | SDAAVDTSSEITTKDLKEKKEVVEEAEN |
| Position of mature hormone in Pre-Hormone protein | 28 Residues from position (2-29) |
| Receptor | N/A |
| Gene ID | 5757 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |