A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 11034 |
| Swiss-prot Accession number | P41547 (Sequence in FASTA format) |
| Description | Calcitonin precursor. |
| Source organism | Canis familiaris (Dog) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
| Subcellular location | Secreted |
| Developmental Stage | N/A |
| Similarity | Belongs to the calcitonin family. |
| Tissue Specificity | Synthesized by C-cells of the thyroid gland |
| Post translational modification | N/A |
| Function | Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones |
| Protein Length | 130 Amino acids |
| Molecular weight | 14051 |
| References | 1 PubMed abstract 10967131 2 PubMed abstract 1758974 |
| Domain Name | Calc_CGRP_IAPP |
| Hormone Name | Calcitonin |
| Mature Hormone Sequence | CSNLSTCVLGTYSKDLNNFHTFSGIGFGAETP |
| Position of mature hormone in Pre-Hormone protein | 32 Residues from position (85-116) |
| Receptor | N/A |
| Gene ID | 403946 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |