A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10941
Swiss-prot Accession numberP11280 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha (Alpha-MSH); Corticotropin-like intermediarypeptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH); Beta-endorphin; Met-enkephalin](Fragment).
Source organismMustela vison (American mink) (Neovison vison)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Mustelidae;Mustelinae; Neovison.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityACTH and MSH are produced by the pituitary gland
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionMet-enkephalin is an endogenous peptide
Protein Length142 Amino acids
Molecular weight15822
References1  PubMed abstract 3397057
2  PubMed abstract 3382437
3  PubMed abstract 3397057
4  PubMed abstract 3382437
Domain NameACTH_domain  Op_neuropeptide  
Hormone NameMet-enkephalin
Mature Hormone SequenceYGGFM
Position of mature hormone in Pre-Hormone protein5 Residues from position (112-116)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated