A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10925
Swiss-prot Accession numberP68001 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin (Pro-opiomelanocortin) (POMC) [Contains:Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanotropin alpha(Alpha-MSH); Corticotropin-like intermediary peptide (CLIP)](Fragment).
Source organismBalaenoptera physalus (Finback whale) (Common rorqual)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Cetacea;Mysticeti; Balaenopteridae; Balaenoptera.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityACTH and MSH are produced by the pituitary gland
Post translational modificationN/A
FunctionMSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes
Protein Length39 Amino acids
Molecular weight4541
References1   Pankov Y.A., Nikolaeva O.P., Elisarova G.P.; "Primary structure of the corticotropin of whalebone whales, finbacks(Balaenoptera physalus)."; Bioorg. Khim. 2:855-856(1976).
2   Pankov Y.A., Nikolaeva O.P., Elisarova G.P.; "Primary structure of the corticotropin of whalebone whales, finbacks(Balaenoptera physalus)."; Bioorg. Khim. 2:855-856(1976).
Domain NameACTH_domain  
Hormone NameMelanotropin alpha (Alpha-MSH)
Mature Hormone SequenceSYSMEHFRWGKPV
Position of mature hormone in Pre-Hormone protein13 Residues from position (1-13)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated