A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 10925 |
| Swiss-prot Accession number | P68001 (Sequence in FASTA format) |
| Description | Corticotropin-lipotropin (Pro-opiomelanocortin) (POMC) [Contains:Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanotropin alpha(Alpha-MSH); Corticotropin-like intermediary peptide (CLIP)](Fragment). |
| Source organism | Balaenoptera physalus (Finback whale) (Common rorqual) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Cetacea;Mysticeti; Balaenopteridae; Balaenoptera. |
| Subcellular location | N/A |
| Developmental Stage | N/A |
| Similarity | Belongs to the POMC family. |
| Tissue Specificity | ACTH and MSH are produced by the pituitary gland |
| Post translational modification | N/A |
| Function | MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes |
| Protein Length | 39 Amino acids |
| Molecular weight | 4541 |
| References | 1 Pankov Y.A., Nikolaeva O.P., Elisarova G.P.; "Primary structure of the corticotropin of whalebone whales, finbacks(Balaenoptera physalus)."; Bioorg. Khim. 2:855-856(1976).
2 Pankov Y.A., Nikolaeva O.P., Elisarova G.P.; "Primary structure of the corticotropin of whalebone whales, finbacks(Balaenoptera physalus)."; Bioorg. Khim. 2:855-856(1976). |
| Domain Name | ACTH_domain |
| Hormone Name | Melanotropin alpha (Alpha-MSH) |
| Mature Hormone Sequence | SYSMEHFRWGKPV |
| Position of mature hormone in Pre-Hormone protein | 13 Residues from position (1-13) |
| Receptor | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |