A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10890
Swiss-prot Accession numberP21563 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismRodentia sp.
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;unclassified rodents.
Subcellular locationSecreted. Note=Stored in spherulous cells prior to secretion
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length108 Amino acids
Molecular weight11849
References1  PubMed abstract 2531072
2   Bairoch A., Duret L.; Unpublished observations (FEB-1996).
3   Mueller W.E.G.; Unpublished observations (APR-1996).
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceIVQQCTSGICSLYQENYCN
Position of mature hormone in Pre-Hormone protein19 Residues from position (90-108)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated