HMRbase accession number | 10775 |
Swiss-prot Accession number | Q7ZZV4 (Sequence in FASTA format) |
Description | Thyrotropin subunit beta precursor (Thyroid-stimulating hormonesubunit beta) (TSH-beta) (TSH-B) (Thyrotropin beta chain). |
Source organism | Anguilla japonica (Japanese eel) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Anguilliformes; Anguillidae;Anguilla. |
Subcellular location | Secreted protein (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the glycoprotein hormones subunit beta family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Indispensable for the control of thyroid structure and metabolism. May play some role in the biological processes of the immature fishes |
Protein Length | 147 Amino acids |
Molecular weight | 16088 |
References | 1 Han Y.-S., Liao I.-C., Tzeng W.-N., Huang Y.-S., Yu J.Y.-L.; "Molecular cloning of the genomic DNA and cDNA encoding thyroidstimulating hormone beta subunit of the Japanese eel and its geneexpression."; Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.
2 Nagae M., Qu X.C., Kazeto Y., Ijiri S., Ito F., Adachi S.,Yamauchi K.; "Molecular cloning of Japanese eel TSH beta."; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
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Domain Name | Cys_knot |
Hormone Name | Thyroid-stimulating hormone subunit beta (TSH-B) (Thyrotropin beta chain) |
Mature Hormone Sequence | ICSPVDYTLYVEKPECDFCVAINTTICMGFCYSLDPNVVGPAVKRLAVQRGCTYQAVEYRTAELPGCPPHVDPRFSYPVALHCTCRACDPARDECTHRASADGDRCSKPLLLHMHAYPGQSNHIQTL |
Position of mature hormone in Pre-Hormone protein | 127 Residues from position (21-147) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |