A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10749
Swiss-prot Accession numberP19795 (Sequence in FASTA format)
DescriptionSomatotropin precursor (Growth hormone).
Source organismMustela vison (American mink)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Mustelidae;Mustelinae; Mustela.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the somatotropin/prolactin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues
Protein Length216 Amino acids
Molecular weight24469
References1  PubMed abstract 2243786
2   Perelygina L.M., Baricheva E.M., Sebeleva T.E., Kokoza V.A.; Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
3  PubMed abstract 2268323
Domain NameHormone_1  
Hormone NameSomatotropin
Mature Hormone SequenceFPAMPLSSLFANAVLRAQHLHQLAADTYKDFERAYIPEGQRYSIQNAQAAFCFSETIPAPTGKDEAQQRSDMELLRFSLLLIQSWLGPVQFLSRVFTNSLVFGTSDRVYEKLKDLEEGIQALMRELEDGSPRAGPILKQTYDKFDTNLRSDDALLKNYGLLSCFKKDLHKAETYLRVMKCRRFVESSCAF
Position of mature hormone in Pre-Hormone protein190 Residues from position (27-216)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated