A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10710
Swiss-prot Accession numberP58757 (Sequence in FASTA format)
DescriptionGrowth hormone variant precursor (GH-V) (Placenta-specific growthhormone) (Growth hormone 2).
Source organismPan troglodytes (Chimpanzee)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the somatotropin/prolactin family.
Tissue SpecificityExpressed in the placenta
Post translational modificationN/A
FunctionPlays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues
Protein Length217 Amino acids
Molecular weight24991
References1   Revol A., Esquivel D., Santiago D., Barrera-Saldana H.; "Independent duplication of the growth hormone gene in threeAnthropoidean lineages."; Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
Domain NameHormone_1  
Hormone NameGrowth hormone variant
Mature Hormone SequenceFPTIPLSRLFDNAMLRAHRLYQLAYDTYQEFEEAYILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLRSVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTKSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
Position of mature hormone in Pre-Hormone protein191 Residues from position (27-217)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated