A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10669
Swiss-prot Accession numberP01302 (Sequence in FASTA format)
DescriptionPancreatic prohormone precursor (Pancreatic polypeptide) (PP)[Contains: Pancreatic hormone; C-terminal peptide 1; C-terminalpeptide 2].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the NPY family.
Tissue SpecificityN/A
Post translational modification N/A
Function Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions
Protein Length131 Amino acids
Molecular weight14376
References1  PubMed abstract 7831336
2   Chance R.E., Moon N.E., Johnson M.G.; (In) Jaffe B.M., Behrman H.R. (eds.);Methods of hormone radioimmunoassay (2nd ed.), pp.657-672, AcademicPress, New York and London (1979).
3  PubMed abstract 1734969
Domain NameHormone_3  
Hormone NamePancreatic hormone
Mature Hormone SequenceAPLEPEYPGDNATPEQMAQYAAELRRYINMLTRPRY
Position of mature hormone in Pre-Hormone protein36 Residues from position (30-65)
ReceptorN/A
Gene IDN/A
PDB ID1BBA   1LJV   1V1D      
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated