A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10603
Swiss-prot Accession numberQ07892 (Sequence in FASTA format)
DescriptionEclosion hormone precursor (Ecdysis activator) (EH).
Source organismDrosophila melanogaster (Fruit fly)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insect eclosion hormone family.
Tissue SpecificityExpressed in a single pair of brain neurons which extend their processes the entire length of the central nervous system and also to the corpora cardiaca portion of the ring gland. These cells show massive depletion of immunoreactive Eh at ecdysis
Post translational modificationN/A
Function Neuropeptide that triggers the performance of ecdysis behaviors at the end of a molt. It triggers adult behavior patterns: larval, pupal and adult ecdysis, and plasticization during the molt
Protein Length97 Amino acids
Molecular weight10610
References1  PubMed abstract 8344291
2  PubMed abstract 10731132
3  PubMed abstract 12537572
4   Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A.,Pacleb J.M., Park S., Wan K.H., Yu C., Celniker S.E.; Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameEclosion  
Hormone NameEclosion hormone
Mature Hormone SequenceLVHFGNALPAISHYTHKRFDSMGGIDFVQVCLNNCVQCKTMLGDYFQGQTCALSCLKFKGKAIPDCEDIASIAPFLNALE
Position of mature hormone in Pre-Hormone protein80 Residues from position (18-97)
ReceptorN/A
Gene ID42101      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated