A database of hormones and their receptors |
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HMRbase accession number | 10588 |
Swiss-prot Accession number | P68000 (Sequence in FASTA format) |
Description | Corticotropin-lipotropin (Pro-opiomelanocortin) (POMC) [Contains:Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanotropin alpha(Alpha-MSH); Corticotropin-like intermediary peptide (CLIP)](Fragment). |
Source organism | Balaenoptera borealis (Sei whale) (Pollack whale) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Cetacea;Mysticeti; Balaenopteridae; Balaenoptera. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the POMC family. |
Tissue Specificity | ACTH and MSH are produced by the pituitary gland |
Post translational modification | N/A |
Function | ACTH stimulates the adrenal glands to release cortisol |
Protein Length | 39 Amino acids |
Molecular weight | 4541 |
References | 1 PubMed abstract 201308 2 PubMed abstract 201308 |
Domain Name | ACTH_domain |
Hormone Name | Corticotropin |
Mature Hormone Sequence | SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF |
Position of mature hormone in Pre-Hormone protein | 39 Residues from position (1-39) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |