A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10585
Swiss-prot Accession numberO77220 (Sequence in FASTA format)
DescriptionCrustacean hyperglycemic hormones precursor [Contains: CHH precursor-related peptide (CPRP); Crustacean hyperglycemic hormone (CHH)].
Source organismMacrobrachium lanchesteri (Prawn)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Caridea;Palaemonoidea; Palaemonidae; Macrobrachium.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
Tissue SpecificityProduced by the medulla terminalis X-organ in the eyestalks and transported to the sinus gland where they are stored and released (By similarity)
Post translational modificationN/A
Function Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction
Protein Length135 Amino acids
Molecular weight15198
References1   Ju B., Khoo H.-W.; "Characterization of crustacean hyperglycemic hormone (CHH) mRNAtranscripts and genomic sequences in Macrobrachium lanchesteri (deMan)."; Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
Domain NameCrust_neurohorm  
Hormone NameCrustacean hyperglycemic hormone
Mature Hormone SequenceAILDQSCKGIFDRELFKKLDRVCDDCYNLYRKPYVAIDCREGCYQNLVFRQCIQDLQLMDQLDEYANAVQIV
Position of mature hormone in Pre-Hormone protein72 Residues from position (62-133)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated