A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 10563 |
| Swiss-prot Accession number | P15410 (Sequence in FASTA format) |
| Description | Bombyxin C-1 precursor (BBX-C1) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin C-1 B chain; Bombyxin C-1 A chain]. |
| Source organism | Bombyx mori (Silk moth) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx. |
| Subcellular location | Secreted protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the insulin family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects |
| Protein Length | 91 Amino acids |
| Molecular weight | 10137 |
| References | 1 Iwami M., Adachi T., Kondo H., Kawakami A., Suzuki Y., Nagasawa H.,Suzuki A., Ishizaki H.; "A novel family C of the genes that encode bombyxin, an insulin-related brain secretory peptide of the silkmoth Bombyx mori: isolationand characterization of gene C-1."; Insect Biochem. 20:295-303(1990).
2 PubMed abstract 8683595 3 PubMed abstract 2708384 |
| Domain Name | Insulin |
| Hormone Name | Bombyxin C-1 B chain |
| Mature Hormone Sequence | QTASQFYCGDFLARTMSSLCWSDMQ |
| Position of mature hormone in Pre-Hormone protein | 25 Residues from position (20-44) |
| Receptor | N/A |
| Gene ID | 100147698 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |