A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10135
Swiss-prot Accession numberP91963 (Sequence in FASTA format)
DescriptionPigment-dispersing hormone type 1 precursor [Contains: PDH precursor-related peptide (PPRD); Pigment-dispersing hormone (PDH)].
Source organismPenaeus vannamei (Penoeid shrimp) (European white shrimp)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata; Penaeoidea;Penaeidae; Litopenaeus.
Subcellular locationSecreted protein (By similarity)
Developmental StageN/A
Similarity Belongs to the arthropod PDH family.
Tissue SpecificityEyestalk
Post translational modificationN/A
FunctionThe pigment-dispersing hormone causes the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas. May also function as a neurotransmitter and/or neuromodulator
Protein Length79 Amino acids
Molecular weight8561
References1  PubMed abstract 8630031
Domain NamePigment_DH  
Hormone NamePigment-dispersing hormone
Mature Hormone SequenceNSELINSLLGIPKVMNDA
Position of mature hormone in Pre-Hormone protein18 Residues from position (59-76)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated