A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10087
Swiss-prot Accession numberQ17192 (Sequence in FASTA format)
DescriptionBombyxin A-1 precursor (BBX-A1) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-1 B chain; Bombyxin A-1 A chain].
Source organismBombyx mori (Silk moth)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects
Protein Length92 Amino acids
Molecular weight10271
References1   Iwami M., Kawakami A., Ishizaki H., Takahashi S.Y., Adachi T.,Suzuki Y., Nagasawa H., Suzuki A.; "Cloning of a gene encoding bombyxin, an insulin-like brain secretorypeptide of the silkmoth Bombyx mori with prothoracicotropicactivity."; Dev. Growth Differ. 31:31-37(1989).
2  PubMed abstract 8683595
Domain NameInsulin  
Hormone NameBombyxin A-1 B chain
Mature Hormone SequenceQQPQRVHTYCGRHLARTLADLCWEAGVD
Position of mature hormone in Pre-Hormone protein28 Residues from position (20-47)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated