A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 10087 |
| Swiss-prot Accession number | Q17192 (Sequence in FASTA format) |
| Description | Bombyxin A-1 precursor (BBX-A1) (4K-prothoracicotropic hormone) (4K-PTTH) [Contains: Bombyxin A-1 B chain; Bombyxin A-1 A chain]. |
| Source organism | Bombyx mori (Silk moth) |
| Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx. |
| Subcellular location | Secreted protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the insulin family. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects |
| Protein Length | 92 Amino acids |
| Molecular weight | 10271 |
| References | 1 Iwami M., Kawakami A., Ishizaki H., Takahashi S.Y., Adachi T.,Suzuki Y., Nagasawa H., Suzuki A.; "Cloning of a gene encoding bombyxin, an insulin-like brain secretorypeptide of the silkmoth Bombyx mori with prothoracicotropicactivity."; Dev. Growth Differ. 31:31-37(1989).
2 PubMed abstract 8683595 |
| Domain Name | Insulin |
| Hormone Name | Bombyxin A-1 B chain |
| Mature Hormone Sequence | QQPQRVHTYCGRHLARTLADLCWEAGVD |
| Position of mature hormone in Pre-Hormone protein | 28 Residues from position (20-47) |
| Receptor | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |