A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 10034 |
| Swiss-prot Accession number | Q9TRM8 (Sequence in FASTA format) |
| Description | Prorelaxin precursor [Contains: Relaxin B chain; Relaxin A chain]. |
| Source organism | Canis familiaris (Dog) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
| Subcellular location | Secreted |
| Developmental Stage | N/A |
| Similarity | Belongs to the insulin family. |
| Tissue Specificity | Placenta; syncytiotrophoblast |
| Post translational modification | N/A |
| Function | Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals |
| Protein Length | 177 Amino acids |
| Molecular weight | 20563 |
| References | 1 PubMed abstract 10026098 2 PubMed abstract 1388669 |
| Domain Name | Insulin |
| Hormone Name | Relaxin B chain |
| Mature Hormone Sequence | TDDKKLKACGRDYVRLQIEVCGSIWWGRKAGQLRE |
| Position of mature hormone in Pre-Hormone protein | 35 Residues from position (26-60) |
| Receptor | Q5XM32
Detail in HMRbase |
| Gene ID | 403742 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |