A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10333
Swiss-prot Accession numberQ8CHK2 (Sequence in FASTA format)
DescriptionRelaxin-3 precursor (Prorelaxin M3) (Insulin-like peptide INSL7)(Insulin-like peptide 7) [Contains: Relaxin-3 B chain; Relaxin-3 Achain].
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityHigh expression in the brain localized to the pons/medulla with highest levels in pars ventromedialis of the dorsal tegmental nucleus. Significant expression is also detected in the spleen, thymus, lung, testis and ovary
Post translational modificationN/A
FunctionMay play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 and relaxin-3 receptor-2
Protein Length141 Amino acids
Molecular weight14926
References1  PubMed abstract 12686464
2  PubMed abstract 11689565
Domain NameInsulin  
Hormone NameRelaxin-3 A chain
Mature Hormone SequenceDVLAGLSSSCCEWGCSKSQISSLC
Position of mature hormone in Pre-Hormone protein24 Residues from position (118-141)
ReceptorQ8BGE9   Detail in HMRbase   
Q7TQP4   Detail in HMRbase   
Q91ZZ5    Detail in HMRbase   
Gene ID212108      
PDB IDN/A
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