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HMRbase accession number | 11396 |
Swiss-prot Accession number | P09683 (Sequence in FASTA format) |
Description | Secretin precursor. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the glucagon family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich bile and inhibits HCl production by the stomach |
Protein Length | 121 Amino acids |
Molecular weight | 13016 |
References | 1 PubMed abstract 11060443 2 Carlquist M., Joernvall H., Forssmann W.-G., Thulin L., Johansson C.,Mutt V.; "Human secretin is not identical to the porcine/bovine hormone."; IRCS Med. Sci. 13:217-218(1985). |
Domain Name | Hormone_2 |
Hormone Name | Secretin |
Mature Hormone Sequence | HSDGTFTSELSRLREGARLQRLLQGLV |
Position of mature hormone in Pre-Hormone protein | 27 Residues from position (28-54) |
Receptor | Q8IV17 Detail in HMRbase P47872 Detail in HMRbase |
Gene ID | 6343 |
PDB ID | N/A |
Drugpedia | wiki |
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