A database of hormones and their receptors
Non-peptide Hormone

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HMRbase accession number1004
PubChem ID6238
Hormone name17-alpha-Hydroxyprogesterone
DescriptionA metabolite of PROGESTERONE with a hydroxyl group at the 17-alpha position. It serves as an intermediate in the biosynthesis of HYDROCORTISONE and GONADAL STEROID HORMONES.
SynonymsProdix Prodox Gestageno gador hydroxyprogesterone Proluton Setaderm Oxiprogesteronum 17-Hydroxyprogesterone 17-alpha-Hydroxyprogesterone Idrossiprogesterone
Molecular weight330.46
Molecular formulaC21H30O3
IUPAC Name(8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Canonical smilesCC(=O)C1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)O
Isomeric smilesCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O
Structure
   
PDB file
SDF file
MOL file
PDB IDN/A
KEGG IDC01176  
HMDB IDHMDB00374
Melting Point222-223(EXP)
Log P3.17(EXP)
Water Solubility6.48(EXP) at 27C
DrugBank IDN/A
Drugpediawiki
ReceptorP06401   Detail in HMRbase   
Q8NG42   Detail in HMRbase   
Q8NG43   Detail in HMRbase   
Q8NG44   Detail in HMRbase   
Q8TDS3   Detail in HMRbase   
Comments
ReferencesPubchem,HMDB