A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10232
Swiss-prot Accession numberQ5R790 (Sequence in FASTA format)
DescriptionProthymosin alpha [Contains: Thymosin alpha].
Source organismPongo pygmaeus (Orangutan)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pongo.
Subcellular locationNucleus (By similarity)
Developmental StageN/A
Similarity Belongs to the pro/parathymosin family.
Tissue SpecificityN/A
Post translational modification Covalently linked to a small RNA of about 20 nucleotides (By similarity).
FunctionProthymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections
Protein Length110 Amino acids
Molecular weight12102
References1   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
Domain NameProthymosin  
Hormone NameThymosin alpha
Mature Hormone SequenceSDAAVDTSSEITTKDLKEKKEVVEEAEN
Position of mature hormone in Pre-Hormone protein28 Residues from position (2-29)
ReceptorN/A
Gene ID100173377      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number11042
Swiss-prot Accession numberP26350 (Sequence in FASTA format)
DescriptionProthymosin alpha [Contains: Thymosin alpha].
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationNucleus
Developmental StageN/A
Similarity Belongs to the pro/parathymosin family.
Tissue SpecificityN/A
Post translational modification Covalently linked to a small RNA of about 20 nucleotides.
FunctionIt is a potent immunopotentiating agent
Protein Length111 Amino acids
Molecular weight12254
References1  PubMed abstract 2015308
2  PubMed abstract 16141072
3  PubMed abstract 15489334
4  PubMed abstract 2226839
5  PubMed abstract 2479575
Domain NameProthymosin  
Hormone NameThymosin alpha
Mature Hormone SequenceSDAAVDTSSEITTKDLKEKKEVVEEAEN
Position of mature hormone in Pre-Hormone protein28 Residues from position (2-29)
ReceptorN/A
Gene ID19231      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number11044
Swiss-prot Accession numberP06302 (Sequence in FASTA format)
DescriptionProthymosin alpha [Contains: Thymosin alpha].
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationNucleus
Developmental StageN/A
Similarity Belongs to the pro/parathymosin family.
Tissue SpecificityN/A
Post translational modification Covalently linked to a small RNA of about 20 nucleotides (By similarity).
Function Thymosin alpha1 (Talpha1) is an oligopeptide hormone originally isolated from the thymus gland, and has been reported to have stimulating effects on the differentiation of T cells and NK cells
Protein Length112 Amino acids
Molecular weight12382
References1  PubMed abstract 3855555
2  PubMed abstract 3377505
3  PubMed abstract 1989881
4  PubMed abstract 15489334
5  PubMed abstract 2269362
Domain NameProthymosin  
Hormone NameThymosin alpha
Mature Hormone SequenceSDAAVDTSSEITTKDLKEKKEVVEEAEN
Position of mature hormone in Pre-Hormone protein28 Residues from position (2-29)
ReceptorN/A
Gene ID29222      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated