A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 10405 |
| Swiss-prot Accession number | P01172 (Sequence in FASTA format) |
| Description | Somatostatin-2 precursor (Somatostatin II) [Contains: Somatostatin-22(SS-22)]. |
| Source organism | Ictalurus punctatus (Channel catfish) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;Ictaluridae; Ictalurus. |
| Subcellular location | Secreted |
| Developmental Stage | N/A |
| Similarity | Belongs to the somatostatin family. |
| Tissue Specificity | Pancreas |
| Post translational modification | O-linked glycan consists of Gal-GalNAc disaccharide which is modified with sialic acid residues (microheterogeneity). |
| Function | Somatostatin inhibits the release of somatotropin |
| Protein Length | 105 Amino acids |
| Molecular weight | 11769 |
| References | 1 PubMed abstract 2863931 2 PubMed abstract 6127673 3 PubMed abstract 6149220 4 PubMed abstract 7358665 |
| Domain Name | N/A |
| Hormone Name | Somatostatin-22 (SS-22) |
| Mature Hormone Sequence | DNTVTSKPLNCMNYFWKSRTAC |
| Position of mature hormone in Pre-Hormone protein | 22 Residues from position (84-105) |
| Receptor | N/A |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments | !Receptor for this Hormone are either unknown or have not yet been curated |