A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10169
Swiss-prot Accession numberP81423 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismAcipenser guldenstadti (Caspian sturgeon) (Russian sturgeon)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Chondrostei; Acipenseriformes; Acipenseridae;Acipenser.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length52 Amino acids
Molecular weight5811
References1  PubMed abstract 9650713
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHSPCSLYDLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (32-52)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10171
Swiss-prot Accession numberQ6YK33 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismGorilla gorilla gorilla (Lowland gorilla)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Gorilla.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight11981
References1  PubMed abstract 12952878
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10174
Swiss-prot Accession numberP81025 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismOreochromis niloticus (Nile tilapia) (Tilapia nilotica)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Tilapiini;Oreochromis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length113 Amino acids
Molecular weight12480
References1  PubMed abstract 9972302
2  PubMed abstract 7656183
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEECCHKPCTIFDLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (93-113)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 4

HMRbase accession number10176
Swiss-prot Accession numberQ9TQY7 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismOrnithorhynchus anatinus (Duckbill platypus)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5854
References1  PubMed abstract 8868070
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEECCKGVCSMYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 5

HMRbase accession number10178
Swiss-prot Accession numberQ98TA8 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismPantodon buchholtzi (Butterflyfish)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Osteoglossomorpha;Osteoglossiformes; Pantodontidae; Pantodon.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight12324
References1  PubMed abstract 11306171
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHHPCNIFDLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 6

HMRbase accession number10180
Swiss-prot Accession numberP81881 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismPiaractus mesopotamicus (Pacu)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;Characidae; Piaractus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length52 Amino acids
Molecular weight5673
References1  PubMed abstract 10327603
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHKPCSIFDLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (32-52)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 7

HMRbase accession number10182
Swiss-prot Accession numberQ8HXV2 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismPongo pygmaeus (Orangutan)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pongo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight12038
References1  PubMed abstract 12952878
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 8

HMRbase accession number10184
Swiss-prot Accession numberQ62587 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismPsammomys obesus (Fat sand rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Gerbillinae; Psammomys.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight12324
References1  PubMed abstract 9166665
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTGICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 9

HMRbase accession number10186
Swiss-prot Accession numberQ91XI3 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismSpermophilus tridecemlineatus (Thirteen-lined ground squirrel)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Sciuridae; Xerinae; Marmotini; Spermophilus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight12004
References1   Tredrea M.M., Buck M.J., Guhaniyogi J., Squire T.L., Andrews M.T.; "Regulation of PDK4 expression in a hibernating mammal."; Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 10

HMRbase accession number10783
Swiss-prot Accession numberP29335 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismAmia calva (Bowfin)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Amiiformes; Amiidae; Amia.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length52 Amino acids
Molecular weight5777
References1  PubMed abstract 2039477
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCLKPCTIYEMEKYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (32-52)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 11

HMRbase accession number10785
Swiss-prot Accession numberP01324 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismAcomys cahirinus (Egyptian spiny mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Deomyinae; Acomys.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5768
References1  PubMed abstract 5028210
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVDQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 12

HMRbase accession number10787
Swiss-prot Accession numberP12703 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismAlligator mississippiensis (American alligator)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Crocodylidae; Alligatorinae; Alligator.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5689
References1  PubMed abstract 6146554
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHNTCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 13

HMRbase accession number10789
Swiss-prot Accession numberP01333 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismAnas platyrhynchos (Domestic duck)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Anseriformes; Anatidae; Anas.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length81 Amino acids
Molecular weight9105
References1  PubMed abstract 4763354
2  PubMed abstract 4715652
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCENPCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (61-81)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 14

HMRbase accession number10791
Swiss-prot Accession numberP42633 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismAnguilla rostrata (American eel)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Anguilliformes; Anguillidae;Anguilla.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5652
References1  PubMed abstract 1874385
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHKPCSIFDLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 15

HMRbase accession number10793
Swiss-prot Accession numberP68245 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismAnser anser anser (Western graylag goose)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Anseriformes; Anatidae; Anser.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5716
References1   Xu Y., Lin N., Zhang Y., Zhang Y.; "Isolation and sequence determination of goose insulin."; Kexue Tongbao 28:966-968(1983).
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCENPCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 16

HMRbase accession number10795
Swiss-prot Accession numberP67972 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismAotus trivirgatus (Night monkey) (Douroucouli)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Aotidae; Aotus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length108 Amino acids
Molecular weight11842
References1  PubMed abstract 3118367
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGVVDQCCTSICSLYQLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (88-108)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 17

HMRbase accession number10797
Swiss-prot Accession numberP01314 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismBalaenoptera borealis (Sei whale) (Pollack whale)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Cetacea;Mysticeti; Balaenopteridae; Balaenoptera.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5724
References1  PubMed abstract 13552701
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCASTCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 18

HMRbase accession number10799
Swiss-prot Accession numberP67973 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismBalaenoptera physalus (Finback whale) (Common rorqual)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Cetacea;Mysticeti; Balaenopteridae; Balaenoptera.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5766
References1  PubMed abstract 14228503
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 19

HMRbase accession number10801
Swiss-prot Accession numberP01317 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Mevtazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length105 Amino acids
Molecular weight11393
References1  PubMed abstract 2456452
2  PubMed abstract 4928892
3  PubMed abstract 14886311
4  PubMed abstract 5545080
5  PubMed abstract 5105368
6  PubMed abstract 13032079
7  PubMed abstract 13249947
8   Smith G.D., Duax W.L., Dodson E.J., Dodson G.G., de Graaf R.A.G.,Reynolds C.D.; "The structure of des-Phe b1 bovine insulin."; Acta Crystallogr. B 38:3028-3032(1982).
9  PubMed abstract 9141131
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCASVCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (85-105)
ReceptorN/A
Gene ID280829      
PDB ID1APH   1BPH   1CPH   1DPH   1HO0   1PID   2A3G   2BN1   2BN3   2INS      
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 20

HMRbase accession number10803
Swiss-prot Accession numberP68243 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismCairina moschata (Muscovy duck)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Anseriformes; Anatidae; Cairina.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5716
References1  PubMed abstract 8759296
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCENPCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 21

HMRbase accession number10805
Swiss-prot Accession numberP13190 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismCallorhynchus milii (Elephant shark) (Elephantfish)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length89 Amino acids
Molecular weight10147
References1   Gieseg M.A., Swarbrick P.A., Perko L., Powell R.J., Cutfield J.F.; "A monobasic proinsulin processing site."; Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 2690815
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHNTCSLVNLEGYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (69-89)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 22

HMRbase accession number10807
Swiss-prot Accession numberP01320 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismCamelus dromedarius (Dromedary) (Arabian camel)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Tylopoda;Camelidae; Camelus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5694
References1   Danho W.O.; "The isolation and characterization of insulin of camel (Camelusdromedarius)."; J. Fac. Med. Baghdad 14:16-28(1972).
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCASVCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 23

HMRbase accession number10809
Swiss-prot Accession numberP01321 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismCanis familiaris (Dog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight12190
References1  PubMed abstract 6296142
2  PubMed abstract 5949593
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorN/A
Gene ID483665      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 24

HMRbase accession number10811
Swiss-prot Accession numberP01319 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismCapra hircus (Goat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Capra.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5692
References1  PubMed abstract 5949593
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCAGVCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 25

HMRbase accession number10813
Swiss-prot Accession numberP01329 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismCavia porcellus (Guinea pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight12187
References1  PubMed abstract 3839794
2  PubMed abstract 6591179
3  PubMed abstract 5949593
4   Smith L.F.; "Amino acid sequences of insulins."; Diabetes 21 Suppl. 2:457-460(1972).
5  PubMed abstract 1158864
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVDQCCTGTCTRHQLQSYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 26

HMRbase accession number10815
Swiss-prot Accession numberP30407 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismCercopithecus aethiops (Green monkey) (Grivet)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight12019
References1  PubMed abstract 1560757
2  PubMed abstract 4626369
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 27

HMRbase accession number10817
Swiss-prot Accession numberP01327 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismChinchilla brevicaudata (Chinchilla)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Chinchillidae; Chinchilla.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length86 Amino acids
Molecular weight9470
References1  PubMed abstract 1175610
2  PubMed abstract 808541
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVDQCCTSICTLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (66-86)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 28

HMRbase accession number10819
Swiss-prot Accession numberP67970 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismGallus gallus (Chicken)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length107 Amino acids
Molecular weight11981
References1  PubMed abstract 7388949
2   Hasegawa S., Honda K., Nata K., Yonekura H., Okamoto H., Hikami Y.; "Isolation of a cDNA encoding chicken insulin precursor."; Anim. Sci. Technol. 62:867-869(1991).
3   Nie Q., Fang M., Sun B., Lei M., Zhang X.; "Complete coding region of chicken preproinsulin gene."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
4  PubMed abstract 5949593
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHNTCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (87-107)
ReceptorN/A
Gene ID396145      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 29

HMRbase accession number10821
Swiss-prot Accession numberP68991 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismChimaera monstrosa (Rabbit fish)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Holocephali; Chimaeriformes; Chimaeridae; Chimaera.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length59 Amino acids
Molecular weight6606
References1  PubMed abstract 3053327
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHNTCSLANLEGYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (39-59)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 30

HMRbase accession number10823
Swiss-prot Accession numberP69047 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismChrysemys dorbigni (Black-bellied slider turtle) (Trachemys dorbigni)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Testudines; Cryptodira; Testudinoidea; Emydidae; Trachemys.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5698
References1  PubMed abstract 1808015
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHNTCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 31

HMRbase accession number10825
Swiss-prot Accession numberP01313 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismCricetulus longicaudatus (Long-tailed hamster) (Chinese hamster)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Cricetulus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight12268
References1  PubMed abstract 6365663
2   Neelon F.A., Delcher H.K., Steinman H., Lebovitz H.E.; "Structure of hamster insulin: comparison with a tumor insulin."; Fed. Proc. 32:300-300(1973).
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVDQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 32

HMRbase accession number10827
Swiss-prot Accession numberP01334 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismCrotalus atrox (Western diamondback rattlesnake)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Scleroglossa; Serpentes; Colubroidea;Viperidae; Crotalinae; Crotalus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5794
References1  PubMed abstract 939409
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCENTCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 33

HMRbase accession number10829
Swiss-prot Accession numberP01335 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismCyprinus carpio (Common carp)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Cyprinus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length108 Amino acids
Molecular weight11821
References1  PubMed abstract 6306593
2  PubMed abstract 7037403
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHKPCSIFELQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (88-108)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 34

HMRbase accession number10831
Swiss-prot Accession numberO73727 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length108 Amino acids
Molecular weight11904
References1  PubMed abstract 9492081
2   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHKPCSIFELQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (88-108)
ReceptorN/A
Gene ID30262      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 35

HMRbase accession number10833
Swiss-prot Accession numberP18109 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismDidelphis marsupialis virginiana (North American opossum)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Didelphimorphia; Didelphidae; Didelphis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5732
References1  PubMed abstract 2695899
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCNSICSLYQLETYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 36

HMRbase accession number10835
Swiss-prot Accession numberP01316 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismElephas maximus (Indian elephant)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Elephas.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5752
References1  PubMed abstract 5949593
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTGVCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 37

HMRbase accession number10837
Swiss-prot Accession numberP06306 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight12069
References1   Okamoto S., Morimatsu M.; "Cat insulin."; Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 3518635
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCASVCSLYQLEHYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorN/A
Gene ID493804      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 38

HMRbase accession number10839
Swiss-prot Accession numberP01336 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismGadus callarias (Baltic cod)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Paracanthopterygii; Gadiformes; Gadidae; Gadus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5789
References1  PubMed abstract 4881974
2  PubMed abstract 4866431
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVDQCCHRPCDIFDLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 39

HMRbase accession number10841
Swiss-prot Accession numberP01310 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length86 Amino acids
Molecular weight9147
References1  PubMed abstract 13373434
2  PubMed abstract 4640931
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTGICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (66-86)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 40

HMRbase accession number10843
Swiss-prot Accession numberP68992 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismHydrolagus colliei (Spotted ratfish) (Pacific ratfish)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Holocephali; Chimaeriformes; Chimaeridae; Hydrolagus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length59 Amino acids
Molecular weight6606
References1  PubMed abstract 3780981
2  PubMed abstract 2646172
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHNTCSLANLEGYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (39-59)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 41

HMRbase accession number10845
Swiss-prot Accession numberP01328 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismHystrix cristata (Crested porcupine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Hystricidae; Hystrix.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5706
References1  PubMed abstract 6995860
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVDQCCTGVCSLYQLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 42

HMRbase accession number10847
Swiss-prot Accession numberP01340 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismKatsuwonus pelamis (Skipjack tuna) (Bonito)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Scombroidei;Scombridae; Katsuwonus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length50 Amino acids
Molecular weight5698
References1  PubMed abstract 14035061
2  PubMed abstract 14036898
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIHZZCCHKPCBIFZLZBYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (30-50)
ReceptorN/A
Gene IDN/A
PDB ID2G56      
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 43

HMRbase accession number10848
Swiss-prot Accession numberP68988 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismLampetra fluviatilis (River lamprey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Hyperoartia;Petromyzontiformes; Petromyzontidae; Lampetra.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length57 Amino acids
Molecular weight6207
References1  PubMed abstract 8575665
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHRKCSIYDMENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (37-57)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 44

HMRbase accession number10850
Swiss-prot Accession numberP09476 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismLepisosteus spatula (Alligator gar) (Atractosteus spatula)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length52 Amino acids
Molecular weight5865
References1  PubMed abstract 3311873
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHKPCTIYELENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (32-52)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 45

HMRbase accession number10852
Swiss-prot Accession numberP69045 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismLophius americanus (American goosefish) (Anglerfish)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Paracanthopterygii; Lophiiformes; Lophiidae; Lophius.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length116 Amino acids
Molecular weight12737
References1  PubMed abstract 7001633
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHRPCNIFDLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (96-116)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 46

HMRbase accession number10854
Swiss-prot Accession numberP69046 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismLophius piscatorius (Allmouth goosefish) (Anglerfish)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Paracanthopterygii; Lophiiformes; Lophiidae; Lophius.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5744
References1  PubMed abstract 5389298
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHRPCNIFDLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 47

HMRbase accession number10856
Swiss-prot Accession numberP30406 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight11991
References1  PubMed abstract 6184262
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 48

HMRbase accession number10858
Swiss-prot Accession numberP67968 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismMeleagris gallopavo (Common turkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Meleagris.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5698
References1  PubMed abstract 5066110
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHNTCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 49

HMRbase accession number10860
Swiss-prot Accession numberP01330 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismMyocastor coypus (Coypu) (Nutria)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Myocastoridae; Myocastor.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5897
References1   Smith L.F.; "Amino acid sequences of insulins."; Diabetes 21 Suppl. 2:457-460(1972).
2  PubMed abstract 3541911
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVDQCCTNICSRNQLMSYCND
Position of mature hormone in Pre-Hormone protein22 Residues from position (30-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 50

HMRbase accession number10862
Swiss-prot Accession numberP07453 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismMyoxocephalus scorpius (Shorthorn sculpin) (Daddy sculpin)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Scorpaeniformes;Cottoidei; Cottidae; Myoxocephalus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length50 Amino acids
Molecular weight5683
References1  PubMed abstract 3525155
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHRPCNIRVLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (30-50)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 51

HMRbase accession number10864
Swiss-prot Accession numberP01342 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismMyxine glutinosa (Atlantic hagfish)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Hyperotreti; Myxiniformes;Myxinidae; Myxininae; Myxine.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length115 Amino acids
Molecular weight12615
References1  PubMed abstract 6265453
2  PubMed abstract 1097441
3  PubMed abstract 4418746
4  PubMed abstract 4427361
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHKRCSIYDLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (95-115)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 52

HMRbase accession number10866
Swiss-prot Accession numberP17715 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismOctodon degus (Degu)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Octodontidae; Octodon.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length109 Amino acids
Molecular weight12197
References1  PubMed abstract 2293024
2  PubMed abstract 2192710
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVDQCCNNICTFNQLQNYCNVP
Position of mature hormone in Pre-Hormone protein23 Residues from position (87-109)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 53

HMRbase accession number10868
Swiss-prot Accession numberP68989 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismOncorhynchus gorbuscha (Pink salmon) (Humpback salmon)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length50 Amino acids
Molecular weight5576
References1   Rusakov Y.I., Karasev V.S., Pertseva M.N., Pankov Y.A.; "Amino acid sequence of humpback salmon (Oncorhynchus gorbuscha)insulin."; Biokhimiia 52:247-254(1987).
2  PubMed abstract 2184990
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHKPCNIFDLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (30-50)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 54

HMRbase accession number10870
Swiss-prot Accession numberP04667 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismOncorhynchus keta (Chum salmon)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length105 Amino acids
Molecular weight11714
References1  PubMed abstract 2757686
2   Sorokin A.V., Skoblov Y.S., Mironov A.A., Zlochevskii M.L.,Dem'Yanova N.G., Rebentish B.A., Kozlov Y.I., Kavsan V.M., Sova V.V.,Debabov V.G.; "Nucleotide sequence of cloned insulin cDNA of Oncorhyncus keta."; Dokl. Biochem. 269:80-83(1983).
3  PubMed abstract 6897724
4   Dem'Yanova N.G., Zlochevskii M.L., Kavsan V.M., Kozlov Y.I.,Petrenko A.I., Polyakova N.E., Prokopenko I.V., Rebentish B.A.,Ryndich A.V., Skoblov Y.S., Sova V.V., Yurin V.L., Yankovskii N.K.,Debabov V.G.; "Cloning of the insulin gene of a fish (Oncorhynchus keta) inEscherichia coli."; Dokl. Biochem. 256:35-38(1981).
5  PubMed abstract 3314270
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHKPCNIFDLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (85-105)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 55

HMRbase accession number10872
Swiss-prot Accession numberP68990 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismOncorhynchus kisutch (Coho salmon)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length50 Amino acids
Molecular weight5576
References1  PubMed abstract 3898237
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHKPCNIFDLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (30-50)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 56

HMRbase accession number10874
Swiss-prot Accession numberP30410 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismPan troglodytes (Chimpanzee)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight12025
References1  PubMed abstract 1560757
2  PubMed abstract 12952878
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorN/A
Gene ID449570      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 57

HMRbase accession number10876
Swiss-prot Accession numberP68987 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismPetromyzon marinus (Sea lamprey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Hyperoartia;Petromyzontiformes; Petromyzontidae; Petromyzon.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length57 Amino acids
Molecular weight6207
References1  PubMed abstract 3282977
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHRKCSIYDMENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (37-57)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 58

HMRbase accession number10878
Swiss-prot Accession numberP67974 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismPhyseter catodon (Sperm whale) (Physeter macrocephalus)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Cetacea;Odontoceti; Physeteridae; Physeter.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5766
References1  PubMed abstract 13373434
2  PubMed abstract 13552701
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 59

HMRbase accession number10880
Swiss-prot Accession numberP01315 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismSus scrofa (Pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length108 Amino acids
Molecular weight11672
References1   Han X.G., Tuch B.E.; "Complete porcine preproinsulin cDNA sequence."; Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 12140686
3  PubMed abstract 14574411
4  PubMed abstract 5657063
5   Chance R.E.; Submitted (JUL-1970) to the PIR data bank.
6   Blundell T.L., Dodson G.G., Hodgkin D., Mercola D.; "Insulin. The structure in the crystal and its reflection in chemistryand biology."; Adv. Protein Chem. 26:279-402(1972).
7   Isaacs N.W., Agarwal R.C.; "Experience with fast Fourier least squares in the refinement of thecrystal structure of rhombohedral 2-zinc insulin at 1.5-Aresolution."; Acta Crystallogr. A 34:782-791(1978).
8  PubMed abstract 2905485
9  PubMed abstract 1772633
10  PubMed abstract 2025410
11  PubMed abstract 15299880
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (88-108)
ReceptorN/A
Gene ID397415      
PDB ID1B17   1B18   1B19   1B2A   1B2B   1B2C   1B2D   1B2E   1B2F   1B2G   1DEI   1IZA   1IZB   1M5A   1MPJ   1SDB   1WAV   1ZEI   1ZNI   2EFA   2G4M   2TCI   3INS   3MTH   4INS   6INS   7INS   9INS      
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 60

HMRbase accession number10882
Swiss-prot Accession numberP09477 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismPlatichthys flesus (European flounder)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Pleuronectiformes;Pleuronectoidei; Pleuronectidae; Platichthys.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5755
References1  PubMed abstract 3556313
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHKPCNIFDLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 61

HMRbase accession number10884
Swiss-prot Accession numberP0C236 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismPolypterus senegalus (Senegal bichir)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Polypteriformes; Polypteridae; Polypterus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length52 Amino acids
Molecular weight5817
References1  PubMed abstract 9446726
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCDTPCSLYDPENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (32-52)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 62

HMRbase accession number10886
Swiss-prot Accession numberP01331 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismProechimys guairae (Casiragua)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Echimyidae; Proechimys.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length50 Amino acids
Molecular weight5707
References1  PubMed abstract 16068186
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVDQCCTNICSRNQLLTYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (30-50)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 63

HMRbase accession number10888
Swiss-prot Accession numberP01311 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismOryctolagus cuniculus (Rabbit)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight11838
References1  PubMed abstract 8132571
2  PubMed abstract 5949593
3   Giddings S.J., Carnaghi L.R., Devaskar S.U.; Submitted (APR-1991) to the EMBL/GenBank/DDBJ databases.
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorN/A
Gene ID100009181      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 64

HMRbase accession number10890
Swiss-prot Accession numberP21563 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismRodentia sp.
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;unclassified rodents.
Subcellular locationSecreted. Note=Stored in spherulous cells prior to secretion
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length108 Amino acids
Molecular weight11849
References1  PubMed abstract 2531072
2   Bairoch A., Duret L.; Unpublished observations (FEB-1996).
3   Mueller W.E.G.; Unpublished observations (APR-1996).
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceIVQQCTSGICSLYQENYCN
Position of mature hormone in Pre-Hormone protein19 Residues from position (90-108)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 65

HMRbase accession number10892
Swiss-prot Accession numberP67971 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismSaimiri sciureus (Common squirrel monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Saimiriinae; Saimiri.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5747
References1  PubMed abstract 2263627
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGVVDQCCTSICSLYQLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 66

HMRbase accession number10894
Swiss-prot Accession numberP51463 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain](Fragment).
Source organismSelasphorus rufus (Hummingbird)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Trochiliformes; Trochilidae; Selasphorus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length103 Amino acids
Molecular weight11378
References1  PubMed abstract 8405887
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHNTCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (83-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 67

HMRbase accession number10896
Swiss-prot Accession numberP01318 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismOvis aries (Sheep)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length105 Amino acids
Molecular weight11235
References1  PubMed abstract 8011164
2  PubMed abstract 13249948
3  PubMed abstract 4626369
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCAGVCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (85-105)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 68

HMRbase accession number10898
Swiss-prot Accession numberP12704 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismSqualus acanthias (Spiny dogfish)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Elasmobranchii; Squalea; Hypnosqualea; Squaliformes; Squaloidei;Squalidae; Squalus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length54 Amino acids
Molecular weight6094
References1  PubMed abstract 6352261
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEHCCHNTCSLYDLEGYCNQ
Position of mature hormone in Pre-Hormone protein22 Residues from position (33-54)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 69

HMRbase accession number10900
Swiss-prot Accession numberP67969 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismStruthio camelus (Ostrich)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Palaeognathae; Struthioniformes; Struthionidae; Struthio.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5698
References1  PubMed abstract 3045031
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHNTCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 70

HMRbase accession number10902
Swiss-prot Accession numberP12705 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain](Fragments).
Source organismTorpedo marmorata (Marbled electric ray)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Elasmobranchii; Squalea; Hypnosqualea; Pristiorajea; Batoidea;Torpediniformes; Torpedinoidei; Torpedinidae; Torpedo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length70 Amino acids
Molecular weight7663
References1  PubMed abstract 3549433
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEHCCHNTCSLFDLEGYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (50-70)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 71

HMRbase accession number10904
Swiss-prot Accession numberP69048 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismTrachemys scripta (Red-eared slider turtle) (Pseudemys scripta)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Testudines; Cryptodira; Testudinoidea; Emydidae; Trachemys.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5698
References1  PubMed abstract 1974347
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHNTCSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 72

HMRbase accession number10905
Swiss-prot Accession numberQ9W7R2 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismVerasper moseri (Barfin flounder)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Pleuronectiformes;Pleuronectoidei; Pleuronectidae; Verasper.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length115 Amino acids
Molecular weight12608
References1   Andoh T., Nagasawa H.; "Two molecular forms of insulin from barfin flounder, Verasper moseri,are derived from a single gene."; Zool. Sci. 15:931-937(1998).
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHKPCNIFDLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (95-115)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 73

HMRbase accession number10907
Swiss-prot Accession numberP12708 (Sequence in FASTA format)
DescriptionInsulin [Contains: Insulin B chain; Insulin A chain].
Source organismZaocys dhumnades (Cantor)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Scleroglossa; Serpentes; Colubroidea;Colubridae; Colubridae incertae sedis; Zaocys.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionInsulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5809
References1  PubMed abstract 7029709
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCENTCSLYELENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 74

HMRbase accession number10912
Swiss-prot Accession numberP01338 (Sequence in FASTA format)
DescriptionInsulin 2 [Contains: Insulin B chain; Insulin A chain].
Source organismBatrachoididae sp. (Toadfish)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Paracanthopterygii; Batrachoididae.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length50 Amino acids
Molecular weight5652
References1  PubMed abstract 5949593
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHRPCDKFDLQSYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (30-50)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 75

HMRbase accession number10914
Swiss-prot Accession numberP01339 (Sequence in FASTA format)
DescriptionInsulin 2 [Contains: Insulin B chain; Insulin A chain].
Source organismThunnus thynnus (Bluefin tuna)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Scombroidei;Scombridae; Thunnus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length51 Amino acids
Molecular weight5742
References1  PubMed abstract 5406482
2   Neumann P.A., Humbel R.E.; Submitted (AUG-1970) to the PIR data bank.
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCHKPCNIFDLQNYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (31-51)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 76

HMRbase accession number11337
Swiss-prot Accession numberP01308 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight11981
References1  PubMed abstract 6243748
2  PubMed abstract 6248962
3  PubMed abstract 503234
4  PubMed abstract 6927840
5  PubMed abstract 8358440
6   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
7  PubMed abstract 15489334
8   Fajardy I.I., Weill J.J., Stuckens C.C., Danze P.M.P.; "Description of a novel RFLP diallelic polymorphism (-127 BsgI C/G)within the 5' region of insulin gene."; Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.
9  PubMed abstract 14426955
10  PubMed abstract 5101771
11  PubMed abstract 5560404
12  PubMed abstract 4443293
13  PubMed abstract 4803504
14  PubMed abstract 4698555
15  PubMed abstract 4698553
16  PubMed abstract 6312455
17  PubMed abstract 6424111
18  PubMed abstract 3470784
19  PubMed abstract 3537011
20  PubMed abstract 2196279
21  PubMed abstract 4019786
22  PubMed abstract 1601997
23  PubMed abstract 2271664
24  PubMed abstract 2036420
25  PubMed abstract 1646635
26  PubMed abstract 1433291
27  PubMed abstract 8421693
28  PubMed abstract 9235985
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCTSICSLYQLENYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorP06213    Detail in HMRbase   
Gene ID3630      
PDB ID1A7F   1AI0   1AIY   1B9E   1BEN   1EFE   1EV3   1EV6   1EVR   1FU2   1FUB   1G7A   1G7B   1GUJ   1HIQ   1HIS   1HIT   1HLS   1HTV   1HUI   1IOG   1IOH   1J73   1JCA   1JCO   1K3M   1KMF   1LKQ   1LPH   1MHI   1MHJ   1MSO   1OS3   1OS4   1QIY   1QIZ   1QJ0   1RWE   1SF1   1SJT   1SJU   1T0C   1T1K   1T1P   1T1Q   1TRZ   1TYL   1TYM   1UZ9   1VKT   1W8P      
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