A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10097
Swiss-prot Accession numberP83486 (Sequence in FASTA format)
DescriptionCrustacean hyperglycemic hormone B (CHHB).
Source organismCherax destructor (Yabbie)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;Parastacoidea; Parastacidae; Cherax.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
Tissue SpecificityN/A
Post translational modification Stereoinversion of L-Phe (in CHHB-I) to D-Phe (in CHHB-II).
FunctionHormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction
Protein Length72 Amino acids
Molecular weight8395
References1  PubMed abstract 15127939
Domain NameCrust_neurohorm  
Hormone NameCrustacean hyperglycemic hormone B
Mature Hormone SequenceQVFDQACKGVYDRAIFKKLDRVCDDCYNLYRKPYVATSCRQNCYSNLVFRQCLDDLLLVDVVDEYVSGVQIV
Position of mature hormone in Pre-Hormone protein72 Residues from position (1-72)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10098
Swiss-prot Accession numberQ25154 (Sequence in FASTA format)
DescriptionCrustacean hyperglycemic hormones isoform B precursor [Contains: CHHprecursor-related peptide B (CPRP-B); Crustacean hyperglycemic hormoneB (CHH-B)].
Source organismHomarus americanus (American lobster)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;Nephropoidea; Nephropidae; Homarus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
Tissue SpecificityProduced by the medulla terminalis X-organ in the eyestalks and transported to the sinus gland where they are stored and released. Present also in the ventral nervous system
Post translational modification Stereoinversion of L-Phe (form CHH-B-I) to D-Phe (form CHH-B- II).
Function Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction
Protein Length134 Amino acids
Molecular weight15050
References1  PubMed abstract 7999796
2  PubMed abstract 1879416
3  PubMed abstract 1788131
4  PubMed abstract 8034574
Domain NameCrust_neurohorm  
Hormone NameCrustacean hyperglycemic hormone B
Mature Hormone SequenceQVFDQACKGVYDRNLFKKLNRVCEDCYNLYRKPFIVTTCRENCYSNRVFRQCLDDLLLSDVIDEYVSNVQMV
Position of mature hormone in Pre-Hormone protein72 Residues from position (61-132)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10517
Swiss-prot Accession numberQ9NGP0 (Sequence in FASTA format)
DescriptionCrustacean hyperglycemic hormones B precursor (CHH-B) (MeCHH-B)[Contains: CHH precursor-related peptide B (CPRP B); Crustaceanhyperglycemic hormone B (CHH B)].
Source organismMetapenaeus ensis (Greasyback shrimp) (Sand shrimp)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata; Penaeoidea;Penaeidae; Metapenaeus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
Tissue SpecificityExpressed at a constant level in the eyestalks of juveniles and mature females. A low level expression is seen in the central nervous system
Post translational modificationN/A
FunctionHormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction
Protein Length113 Amino acids
Molecular weight12937
References1  PubMed abstract 10781818
Domain NameN/A
Hormone NameCrustacean hyperglycemic hormone B
Mature Hormone SequenceSLFDPSCTGVFDRELLGRLNRVCDDCYNVFREPKVATECRSHCFLNPAFIQCLEYIIPEVLHEEYQANVQLV
Position of mature hormone in Pre-Hormone protein72 Residues from position (40-111)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated