A database of hormones and their receptors |
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HMRbase accession number | 10097 |
Swiss-prot Accession number | P83486 (Sequence in FASTA format) |
Description | Crustacean hyperglycemic hormone B (CHHB). |
Source organism | Cherax destructor (Yabbie) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;Parastacoidea; Parastacidae; Cherax. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the arthropod CHH/MIH/GIH/VIH hormone family. |
Tissue Specificity | N/A |
Post translational modification | Stereoinversion of L-Phe (in CHHB-I) to D-Phe (in CHHB-II). |
Function | Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction |
Protein Length | 72 Amino acids |
Molecular weight | 8395 |
References | 1 PubMed abstract 15127939 |
Domain Name | Crust_neurohorm |
Hormone Name | Crustacean hyperglycemic hormone B |
Mature Hormone Sequence | QVFDQACKGVYDRAIFKKLDRVCDDCYNLYRKPYVATSCRQNCYSNLVFRQCLDDLLLVDVVDEYVSGVQIV |
Position of mature hormone in Pre-Hormone protein | 72 Residues from position (1-72) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10098 |
Swiss-prot Accession number | Q25154 (Sequence in FASTA format) |
Description | Crustacean hyperglycemic hormones isoform B precursor [Contains: CHHprecursor-related peptide B (CPRP-B); Crustacean hyperglycemic hormoneB (CHH-B)]. |
Source organism | Homarus americanus (American lobster) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;Nephropoidea; Nephropidae; Homarus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the arthropod CHH/MIH/GIH/VIH hormone family. |
Tissue Specificity | Produced by the medulla terminalis X-organ in the eyestalks and transported to the sinus gland where they are stored and released. Present also in the ventral nervous system |
Post translational modification | Stereoinversion of L-Phe (form CHH-B-I) to D-Phe (form CHH-B- II). |
Function | Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction |
Protein Length | 134 Amino acids |
Molecular weight | 15050 |
References | 1 PubMed abstract 7999796 2 PubMed abstract 1879416 3 PubMed abstract 1788131 4 PubMed abstract 8034574 |
Domain Name | Crust_neurohorm |
Hormone Name | Crustacean hyperglycemic hormone B |
Mature Hormone Sequence | QVFDQACKGVYDRNLFKKLNRVCEDCYNLYRKPFIVTTCRENCYSNRVFRQCLDDLLLSDVIDEYVSNVQMV |
Position of mature hormone in Pre-Hormone protein | 72 Residues from position (61-132) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10517 |
Swiss-prot Accession number | Q9NGP0 (Sequence in FASTA format) |
Description | Crustacean hyperglycemic hormones B precursor (CHH-B) (MeCHH-B)[Contains: CHH precursor-related peptide B (CPRP B); Crustaceanhyperglycemic hormone B (CHH B)]. |
Source organism | Metapenaeus ensis (Greasyback shrimp) (Sand shrimp) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata; Penaeoidea;Penaeidae; Metapenaeus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the arthropod CHH/MIH/GIH/VIH hormone family. |
Tissue Specificity | Expressed at a constant level in the eyestalks of juveniles and mature females. A low level expression is seen in the central nervous system |
Post translational modification | N/A |
Function | Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level. Has a secretagogue action over the amylase released from the midgut gland. May act as a stress hormone and may be involved in the control of molting and reproduction |
Protein Length | 113 Amino acids |
Molecular weight | 12937 |
References | 1 PubMed abstract 10781818 |
Domain Name | N/A |
Hormone Name | Crustacean hyperglycemic hormone B |
Mature Hormone Sequence | SLFDPSCTGVFDRELLGRLNRVCDDCYNVFREPKVATECRSHCFLNPAFIQCLEYIIPEVLHEEYQANVQLV |
Position of mature hormone in Pre-Hormone protein | 72 Residues from position (40-111) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |