A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21277 |
| Swiss-prot Accession number | Q9XSB5 (Sequence in FASTA format) |
| Description | RecName: Estrogen receptor beta;ER-beta;Alternative Name: Nuclear receptor subfamily 3 group A member 2; |
| Source organism | Bos taurus (Bovine) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Present in granulosa cells of antral follicles in various stages of follicular growth. |
| Post translational modification | N/A |
| Function | Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation. |
| Protein Length | 527 Amino acids |
| Molecular weight | 59032 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 10026117 2 PubMed abstract 10432221 |
| Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
| Gene ID | 281146 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |