A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21199 |
| Swiss-prot Accession number | Q9TU31 (Sequence in FASTA format) |
| Description | Parathyroid hormone/parathyroid hormone-related peptide receptorprecursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor). |
| Source organism | Canis familiaris (Dog) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
| Subcellular location | Membrane; multi-pass membrane protein |
| Developmental Stage | N/A |
| Similarity | Belongs to the G-protein coupled receptor 2 family. |
| Tissue Specificity | High levels in the kidney, with much lower levels in aorta, heart, lung, prostate, testis, and skeletal muscle. |
| Post translational modification | N/A |
| Function | This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system (By similarity). |
| Protein Length | 595 Amino acids |
| Molecular weight | 66309 |
| Domain Name | 7tm_2 HRM |
| References | 1 PubMed abstract 12153143 2 PubMed abstract 12153143 |
| Hormone | P52212 Detail in HMRbase |
| Gene ID | 403779 |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |