A database of hormones and their receptors| A database of hormones and their receptors |
|
|
|
|
|
|
|
| HMRbase accession number | 21275 |
| Swiss-prot Accession number | Q9IAL9 (Sequence in FASTA format) |
| Description | RecName: Estrogen receptor beta-2;ER-beta-2;Alternative Name: Nuclear receptor subfamily 3 group A member 2-B; |
| Source organism | Carassius auratus (Goldfish) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Predominantly expressed in pituitary, telencephalon and hypothalamus as well as in the liver. |
| Post translational modification | N/A |
| Function | Binds estrogens with an affinity similar to that of ER- alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. |
| Protein Length | 610 Amino acids |
| Molecular weight | 67852 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 10786629 |
| Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |