A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21208 |
| Swiss-prot Accession number | Q8MIK0 (Sequence in FASTA format) |
| Description | RecName: Androgen receptor;Alternative Name: Dihydrotestosterone receptor;Alternative Name: Nuclear receptor subfamily 3 group C member 4; |
| Source organism | Crocuta crocuta (Spotted hyena) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Hyaenidae;Crocuta. |
| Subcellular location | Nucleus (By similarity) |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 (By similarity). |
| Protein Length | 912 Amino acids |
| Molecular weight | 99958 |
| Domain Name | Androgen_recep Hormone_recep zf-C4 |
| References | 1 PubMed abstract 12242031 |
| Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
| Gene ID | N/A |
| PDB ID | N/A |
| Drugpedia | wiki |
| Comments |