![]() |
|
|
|
|
|
|
HMRbase accession number | 21641 |
Swiss-prot Accession number | Q13258 (Sequence in FASTA format) |
Description | Prostaglandin D2 receptor;Alternative Name: Prostanoid DP receptor;Alternative Name: PGD receptor |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in retina and small intestine. |
Post translational modification | N/A |
Function | Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate. |
Protein Length | 359 Amino acids |
Molecular weight | 40271 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7642548 2 PubMed abstract 15489334 3 PubMed abstract 15496624 |
Hormone | Detail in HMRbase |
Gene ID | 5729 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |