A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10005
Swiss-prot Accession numberP81278 (Sequence in FASTA format)
DescriptionProlactin-releasing peptide precursor (PrRP) (Prolactin-releasinghormone) [Contains: Prolactin-releasing peptide PrRP31; Prolactin-releasing peptide PrRP20].
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity N/A
Tissue SpecificityWidely expressed, with highest levels in medulla oblongata and hypothalamus
Post translational modificationN/A
FunctionStimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL
Protein Length83 Amino acids
Molecular weight9215
References1  PubMed abstract 9607765
2  PubMed abstract 11178959
3   Anderson S.T., Kokay I.C., Lang T., Grattan D.R., Curlewis J.D.; "Quantitation of prolactin-releasing peptide (PrRP) mRNA expression inspecific brain regions during the rat oestrous cycle and inlactation."; Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
4  PubMed abstract 10498338
Domain NameN/A
Hormone NameProlactin-releasing peptide PrRP31
Mature Hormone SequenceSRAHQHSMETRTPDINPAWYTGRGIRPVGRF
Position of mature hormone in Pre-Hormone protein31 Residues from position (22-52)
ReceptorQ64121    Detail in HMRbase   
Gene ID63850      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 2

HMRbase accession number10307
Swiss-prot Accession numberP81278 (Sequence in FASTA format)
DescriptionProlactin-releasing peptide precursor (PrRP) (Prolactin-releasinghormone) [Contains: Prolactin-releasing peptide PrRP31; Prolactin-releasing peptide PrRP20].
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity N/A
Tissue SpecificityWidely expressed, with highest levels in medulla oblongata and hypothalamus
Post translational modificationN/A
FunctionStimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL
Protein Length83 Amino acids
Molecular weight9215
References1  PubMed abstract 9607765
2  PubMed abstract 11178959
3   Anderson S.T., Kokay I.C., Lang T., Grattan D.R., Curlewis J.D.; "Quantitation of prolactin-releasing peptide (PrRP) mRNA expression inspecific brain regions during the rat oestrous cycle and inlactation."; Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
4  PubMed abstract 10498338
Domain NameN/A
Hormone NameProlactin-releasing peptide PrRP20
Mature Hormone SequenceTPDINPAWYTGRGIRPVGRF
Position of mature hormone in Pre-Hormone protein20 Residues from position (33-52)
ReceptorQ64121    Detail in HMRbase   
Gene ID63850      
PDB IDN/A
Drugpediawiki
Comments