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HMRbase accession number | 11492 |
Swiss-prot Accession number | P62969 (Sequence in FASTA format) |
Description | Thyroliberin (Thyrotropin-releasing hormone) (TRH) (Thyrotropin-releasing factor) (TRF) (TSH-releasing factor) (Protirelin). |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the TRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems |
Protein Length | 3 Amino acids |
Molecular weight | 380 |
References | 1 Desiderio D.M. Jr., Burgus R., Dunn T.F., Vale W., Guillemin R.,Ward D.N.; "The elucidation of the primary structure of the hypothalamic thyroidstimulating hormone releasing factor of ovine origin by means of massspectrometry."; Org. Mass Spectrom. 5:221-228(1971).
2 PubMed abstract 4985794 |
Domain Name | N/A |
Hormone Name | Thyroliberin |
Mature Hormone Sequence | QHP |
Position of mature hormone in Pre-Hormone protein | 3 Residues from position (1-3) |
Receptor | Q28596
Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
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