A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21355 |
| Swiss-prot Accession number | P55055 (Sequence in FASTA format) |
| Description | RecName: Oxysterols receptor LXR-beta;Alternative Name: Liver X receptor beta;Alternative Name: Nuclear orphan receptor LXR-beta;Alternative Name: Nuclear receptor subfamily 1 group H member 2;Alternative Name: Ubiquitously-expressed nuclear receptor;Alternative Name: Nuclear receptor NER; |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Nucleus (Potential) |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | Ubiquitous. |
| Post translational modification | N/A |
| Function | Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). |
| Protein Length | 461 Amino acids |
| Molecular weight | 51102 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 7926814 2 PubMed abstract 14702039 3 PubMed abstract 15489334 4 PubMed abstract 12819202 |
| Hormone | Detail in HMRbase Detail in HMRbase |
| Gene ID | 7376 |
| PDB ID | 1P8D 1PQ6 1PQ9 1PQC 1UPV 1UPW |
| Drugpedia | wiki |
| Comments |