A database of hormones and their receptors| A database of hormones and their receptors |
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| HMRbase accession number | 21506 |
| Swiss-prot Accession number | P11473 (Sequence in FASTA format) |
| Description | Vitamin D3 receptor;VDR;Alternative Name: 1,25-dihydroxyvitamin D3 receptor;Alternative Name: Nuclear receptor subfamily 1 group I member 1 |
| Source organism | Homo sapiens (Human) |
| Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
| Subcellular location | Nucleus |
| Developmental Stage | N/A |
| Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
| Tissue Specificity | N/A |
| Post translational modification | N/A |
| Function | Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Plays a central role in calcium homeostasis. |
| Protein Length | 427 Amino acids |
| Molecular weight | 48289 |
| Domain Name | Hormone_recep zf-C4 |
| References | 1 PubMed abstract 2835767 2 PubMed abstract 1324736 3 PubMed abstract 9212063 4 PubMed abstract 15489334 5 PubMed abstract 1850412 6 PubMed abstract 9267036 7 PubMed abstract 10866662 8 PubMed abstract 10678179 9 PubMed abstract 11344298 10 PubMed abstract 11980721 11 PubMed abstract 15055995 12 PubMed abstract 15225774 13 PubMed abstract 15728261 14 PubMed abstract 16913708 15 PubMed abstract 2849209 16 PubMed abstract 8381803 17 PubMed abstract 1652893 18 PubMed abstract 2177843 19 PubMed abstract 8106618 20 PubMed abstract 8392085 21 PubMed abstract 7828346 22 PubMed abstract 8675579 23 PubMed abstract 8961271 24 PubMed abstract 9005998 25 PubMed abstract 15032981 |
| Hormone | Detail in HMRbase Detail in HMRbase |
| Gene ID | 7421 |
| PDB ID | 1DB1 1IE8 1IE9 1KB2 1KB4 1KB6 1S0Z 1S19 1TXI 1YNW 2HAM 2HAR 2HAS 2HB7 2HB8 |
| Drugpedia | wiki |
| Comments |