A database of hormones and their receptors |
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HMRbase accession number | 11387 |
Swiss-prot Accession number | P07492 (Sequence in FASTA format) |
Description | Gastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10)]. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the bombesin/neuromedin-B/ranatensin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | GRP stimulates gastrin release as well as other gastrointestinal hormones |
Protein Length | 148 Amino acids |
Molecular weight | 16144 |
References | 1 PubMed abstract 3001723 2 PubMed abstract 3211139 3 PubMed abstract 3003116 4 PubMed abstract 15489334 |
Domain Name | Bombesin |
Hormone Name | Gastrin-releasing peptide |
Mature Hormone Sequence | VPLPAGGGTVLTKMYPRGNHWAVGHLM |
Position of mature hormone in Pre-Hormone protein | 27 Residues from position (24-50) |
Receptor | P30550
Detail in HMRbase |
Gene ID | 2922 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11388 |
Swiss-prot Accession number | P07492 (Sequence in FASTA format) |
Description | Gastrin-releasing peptide precursor (GRP) [Contains: Neuromedin-C(GRP-10)]. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the bombesin/neuromedin-B/ranatensin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | It is also a bombesin-like peptide, which causes potent stimulation of smooth muscle of uterus. |
Protein Length | 148 Amino acids |
Molecular weight | 16144 |
References | 1 PubMed abstract 3001723 2 PubMed abstract 3211139 3 PubMed abstract 3003116 4 PubMed abstract 15489334 |
Domain Name | Bombesin |
Hormone Name | Neuromedin-C |
Mature Hormone Sequence | GNHWAVGHLM |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (41-50) |
Receptor | P30550
Detail in HMRbase |
Gene ID | 2922 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |