A database of hormones and their receptors
Non-peptide Hormone

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HMRbase accession number1071
PubChem ID9878
Hormone nameFluorometholone
DescriptionA glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
SynonymsFluorometholone Oxylone Flumetholon Cortilet Delmeson Trilcin FML Liquifilm Fluormetholonum
Molecular weight376.46
Molecular formulaC22H29FO4
IUPAC Name(6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Canonical smilesCC1CC2C3CCC(C3(CC(C2(C4(C1=CC(=O)C=C4)C)F)O)C)(C(=O)C)O
Isomeric smilesC[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@]2([C@@]4(C1=CC(=O)C=C4)C)F)O)C)(C(=O)C)O
Structure
   
PDB file
SDF file
MOL file
PDB IDN/A
KEGG IDD01367   
HMDB IDN/A
Melting Point297(EXP)
Log P2(EXP)
Water Solubility30(EXP) at 25C
DrugBank IDDB00324
Drugpediawiki
ReceptorP59667   Detail in HMRbase   
Comments
ReferencesPubchem