Mapping of Experimentally Validated Epitopes
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This page maintain experimentally valiadted epitopes (B-cell, T-cell) of coronavirus. In order to obtain these epitope, we map epitopes in Immune Epitope Database (IEDB) on proteins of coronavirus. IEDB is a repository of experimentally validated epitopes. Following table provides protein name of COVID-19, amino acid sequence of epitope, B-cell assay and T-cell assay. B-cell and T-cell assay shows the pubmed ID, epitope description, host organism, Method/Technique, Assay Group, and Qualitative Measure.
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| Protein Name | Epitope | B-cell Assay |
|---|---|---|
| Membrane Glycoprotein | LMESELVIGAVIIRGHLR | 16081901; LMESELVIGAVIIRGHLR; Homo sapiens; ELISA; qualitative binding; Positive |
| Membrane Glycoprotein | GRCDIKDLPKEITVATSR | 16081901; GRCDIKDLPKEITVATSR; Homo sapiens; ELISA; qualitative binding; Positive |
| Membrane Glycoprotein | PKEITVATSRTLSYYKL | 16081901; PKEITVATSRTLSYYKL; Homo sapiens; ELISA; qualitative binding; Positive |
| Membrane Glycoprotein | TSRTLSYYKLGASQRV | 16081901; TSRTLSYYKLGASQRV; Homo sapiens; ELISA; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | RPKQRRPQGLPNNTASWF | 15528730; RPKQRRPQGLPNNTASWF; Homo sapiens; ELISA; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | RPKQRRPQGLPNNTASWF | 15528730; RPKQRRPQGLPNNTASWF; Homo sapiens; ELISA; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | PKQRRPQGLPNNTASWFT | 16461566; PKQRRPQGLPNNTASWFT; Homo sapiens; immuno staining; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | GLPNNTASWFTALTQHGK | 15528730; GLPNNTASWFTALTQHGK; Homo sapiens; ELISA; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | WFTALTQHGKEELRFPR | 15528730; WFTALTQHGKEELRFPR; Homo sapiens; ELISA; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | HGKEELRFPRGQGVPI | 15528730; HGKEELRFPRGQGVPI; Homo sapiens; ELISA; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | RFPRGQGVPINTNSGPDDQI | 15528730; RFPRGQGVPINTNSGPDDQI; Homo sapiens; ELISA; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | NTNSGPDDQIGYYRRATR | 15528730; NTNSGPDDQIGYYRRATR; Homo sapiens; ELISA; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | AATVLQLPQGTTLPK | 15528730; AATVLQLPQGTTLPK; Homo sapiens; ELISA; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | KKSAAEASKKPRQKRTA | 15528730; KKSAAEASKKPRQKRTA; Homo sapiens; ELISA; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | RGPEQTQGNFGDQDLIR | 15528730; RGPEQTQGNFGDQDLIR; Homo sapiens; ELISA; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | FFGMSRIGMEVTPSGTW | 15528730; FFGMSRIGMEVTPSGTW; Homo sapiens; ELISA; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | MEVTPSGTWLTYHGAIK | 15528730; MEVTPSGTWLTYHGAIK; Homo sapiens; ELISA; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | QFKDNVILLNKHIDAYK | 15528730; QFKDNVILLNKHIDAYK; Homo sapiens; ELISA; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | LNKHIDAYKTFPPTEPK | 15528730; LNKHIDAYKTFPPTEPK; Homo sapiens; ELISA; qualitative binding; Positive |
| Nucleocapsid Phosphoprotein | KTFPPTEPKKDKKKK | 15528730; KTFPPTEPKKDKKKK; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | VRFPNITNLCPFGEVFN | 15356154; VRFPNITNLCPFGEVFN; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | VYAWERKKISNCVADYSVLYNSTF | 19951177; VYAWERKKISNCVADYSVLYNSTF; Mus musculus BALB/c; immuno staining; qualitative binding; Positive |
| Surface Glycoprotein | GYQPYRVVVLSFELLNAPATV | 15655773; GYQPYRVVVLSFELLNAPATV; Mus musculus HuMAb (Medarex); flow cytometry; qualitative binding; Positive |
| Surface Glycoprotein | SSEVAVLYQDVNCTDV | 16101348; SSEVAVLYQDVNCTDV; Gallus gallus; ELISA; qualitative binding; Positive-Intermediate |
| Surface Glycoprotein | CANLLLQYGSFCTQLNRALSGIA | 15811330; CANLLLQYGSFCTQLNRALSGIA; Oryctolagus cuniculus New Zealand White; western blot; qualitative binding; Positive |
| Surface Glycoprotein | RSFIEDLLFNKVTLADAGFMKQYGECLGDINARDLICAQKFNGLTVLP | 15194770; RSFIEDLLFNKVTLADAGFMKQYGECLGDINARDLICAQKFNGLTVLP; Oryctolagus cuniculus New Zealand White; western blot; qualitative binding; Positive |
| Surface Glycoprotein | TAGWTFGAGAALQIPFA | 15356154; TAGWTFGAGAALQIPFA; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | GAALQIPFAMQMAYRFN | 15356154; GAALQIPFAMQMAYRFN; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | PFAMQMAYRFNGIGVTQ | 15356154; PFAMQMAYRFNGIGVTQ; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | MAYRFNGIGVTQNVLYE | 15356154; MAYRFNGIGVTQNVLYE; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | GIGVTQNVLYENQKQIA | 15356154; GIGVTQNVLYENQKQIA; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | TALGKLQDVVNQNAQAL | 15356154; TALGKLQDVVNQNAQAL; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | DVVNQNAQALNTLVKQL | 15356154; DVVNQNAQALNTLVKQL; Mus musculus BALB/c; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | QALNTLVKQLSSNFGAI | 15356154; QALNTLVKQLSSNFGAI; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | KQLSSNFGAISSVLNDI | 15356154; KQLSSNFGAISSVLNDI; Mus musculus BALB/c; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | AISSVLNDILSRLDKVE | 15356154; AISSVLNDILSRLDKVE; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | ILSRLDKVEAEVQIDRL | 15356154; ILSRLDKVEAEVQIDRL; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | EAEVQIDRLITGRLQSL | 15356154; EAEVQIDRLITGRLQSL; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | RLITGRLQSLQTYVTQQ | 15356154; RLITGRLQSLQTYVTQQ; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | SLQTYVTQQLIRAAEIR | 15356154; SLQTYVTQQLIRAAEIR; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | QLIRAAEIRASANLAAT | 15356154; QLIRAAEIRASANLAAT; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | RASANLAATKMSECVLG | 15356154; RASANLAATKMSECVLG; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | AATKMSECVLGQSKRVD | 15356154; AATKMSECVLGQSKRVD; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | VLGQSKRVDFCGKGYHL | 15356154; VLGQSKRVDFCGKGYHL; Oryctolagus cuniculus New Zealand White; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | DFCGKGYHLMSFPQAAP | 15356154; DFCGKGYHLMSFPQAAP; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | LMSFPQAAPHGVVFLHV | 15356154; LMSFPQAAPHGVVFLHV; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | FFSPQIITTDNTFVSGNCDVVIGIINNTVYDPLQPELDSF | 16378996; FFSPQIITTDNTFVSGNCDVVIGIINNTVYDPLQPELDSF; Mus musculus BALB/c; western blot; qualitative binding; Positive |
| Surface Glycoprotein | VIGIINNTVYDPLQPELDSF | 16378996; VIGIINNTVYDPLQPELDSF; Mus musculus BALB/c; western blot; qualitative binding; Positive |
| Surface Glycoprotein | TVYDPLQPELDSFKEEL | 15356154; TVYDPLQPELDSFKEEL; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | PELDSFKEELDKYFKNH | 15356154; PELDSFKEELDKYFKNH; Mus musculus BALB/c; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | EELDKYFKNHTSPDVDL | 15356154; EELDKYFKNHTSPDVDL; Mus musculus BALB/c; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | KNHTSPDVDLGDISGIN | 15356154; KNHTSPDVDLGDISGIN; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | DLGDISGINASVVNIQK | 15356154; DLGDISGINASVVNIQK; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | KEIDRLNEVAKNLNESL | 15356154; KEIDRLNEVAKNLNESL; Mus musculus BALB/c; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | EVAKNLNESLIDLQELG | 15356154; EVAKNLNESLIDLQELG; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | PWYVWLGFIAGLIAIVM | 15356154; PWYVWLGFIAGLIAIVM; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | IAGLIAIVMVTILLCCM | 15356154; IAGLIAIVMVTILLCCM; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | MVTILLCCMTSCCSCLK | 15356154; MVTILLCCMTSCCSCLK; Homo sapiens; ELISA; qualitative binding; Positive |
| Surface Glycoprotein | CKFDEDDSEPVLKGVKLHYT | 16461566; CKFDEDDSEPVLKGVKLHYT; Homo sapiens; immuno staining; qualitative binding; Positive |
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