Mapping of Experimentally Validated Epitopes
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This page maintain experimentally valiadted epitopes (B-cell, T-cell) of coronavirus. In order to obtain these epitope, we map epitopes in Immune Epitope Database (IEDB) on proteins of coronavirus. IEDB is a repository of experimentally validated epitopes. Following table provides protein name of SARS-COV-2, amino acid sequence of epitope, B-cell assay and T-cell assay. B-cell and T-cell assay shows the pubmed ID, epitope description, host organism, Method/Technique, Assay Group, and Qualitative Measure.
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| Protein Name | Epitope | B-cell Assay | T-cell Assay |
|---|---|---|---|
| Nucleocapsid Phosphoprotein | IVWVATEGALNTPKDHI | 15528730; IVWVATEGALNTPKDHI; Homo sapiens; ELISA; qualitative binding; Positive | 19727132; IVWVATEGALNTPKDHI; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | QLPQGTTLPKGFYAEGSR | 15528730; QLPQGTTLPKGFYAEGSR; Homo sapiens; ELISA; qualitative binding; Positive | 19727132; QLPQGTTLPKGFYAEGSR; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | PKGFYAEGSRGGSQASSR | 15528730; PKGFYAEGSRGGSQASSR; Homo sapiens; ELISA; qualitative binding; Positive | 19727132; PKGFYAEGSRGGSQASSR; Mus musculus BALB/c; ELISPOT; IFNg release; Positive |
| Nucleocapsid Phosphoprotein | SRGGSQASSRSSSRSR | 15528730; SRGGSQASSRSSSRSR; Homo sapiens; ELISA; qualitative binding; Positive | 19727132; SRGGSQASSRSSSRSR; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | ALALLLLDRLNQLESKV | 15528730; ALALLLLDRLNQLESKV; Homo sapiens; ELISA; qualitative binding; Positive | 19727132; ALALLLLDRLNQLESKV; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | KVSGKGQQQQGQTVTKK | 15528730; KVSGKGQQQQGQTVTKK; Homo sapiens; ELISA; qualitative binding; Positive | 19727132; KVSGKGQQQQGQTVTKK; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | QQQGQTVTKKSAAEASKK | 15528730; QQQGQTVTKKSAAEASKK; Homo sapiens; ELISA; qualitative binding; Positive | 19727132; QQQGQTVTKKSAAEASKK; Mus musculus BALB/c; ELISPOT; IFNg release; Positive-Low |
| Nucleocapsid Phosphoprotein | SKKPRQKRTATKQYNV | 15528730; SKKPRQKRTATKQYNV; Homo sapiens; ELISA; qualitative binding; Positive | 19727132; SKKPRQKRTATKQYNV; Mus musculus BALB/c; ELISPOT; IFNg release; Positive-Low |
| Nucleocapsid Phosphoprotein | KRTATKQYNVTQAFGRR | 15528730; KRTATKQYNVTQAFGRR; Homo sapiens; ELISA; qualitative binding; Positive | 19727132; KRTATKQYNVTQAFGRR; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | YNVTQAFGRRGPEQTQGNF | 15528730; YNVTQAFGRRGPEQTQGNF; Homo sapiens; ELISA; qualitative binding; Positive | 19727132; YNVTQAFGRRGPEQTQGNF; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | GNFGDQDLIRQGTDYKHW | 15528730; GNFGDQDLIRQGTDYKHW; Homo sapiens; ELISA; qualitative binding; Positive | 19727132; GNFGDQDLIRQGTDYKHW; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | IRQGTDYKHWPQIAQFA | 15528730; IRQGTDYKHWPQIAQFA; Homo sapiens; ELISA; qualitative binding; Positive | 19727132; IRQGTDYKHWPQIAQFA; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | KHWPQIAQFAPSASAFF | 15528730; KHWPQIAQFAPSASAFF; Homo sapiens; ELISA; qualitative binding; Positive | 19727132; KHWPQIAQFAPSASAFF; Mus musculus BALB/c; ELISPOT; IFNg release; Positive-Low |
| Nucleocapsid Phosphoprotein | QFAPSASAFFGMSRIGM | 15528730; QFAPSASAFFGMSRIGM; Homo sapiens; ELISA; qualitative binding; Positive | 19727132; QFAPSASAFFGMSRIGM; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
|| CoronaVir || India_MOHFW || WHO Advisory || Status || Diagnostics Tests || Genome || Patient Mangagement || Drug Design || Raghava's Group ||
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