Mapping of Experimentally Validated Epitopes
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This page maintain experimentally valiadted epitopes (B-cell, T-cell) of corona virus. In order to obtain these epitope, we map epitopes in Immune Epitope Database (IEDB) on proteins of coronavirus. IEDB is a repository of experimentally validated epitopes. Following table provides protein name of COVID-19, amino acid sequence of epitope, B-cell assay and T-cell assay. B-cell and T-cell assay shows the pubmed ID, epitope description, host organism, Method/Technique, Assay Group, and Qualitative Measure.
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| Protein Name | Epitope | T-cell Assay |
|---|---|---|
| ORF6 | MFHLVDFQVTIAEIL | 26954467; MFHLVDFQVTIAEIL; Homo sapiens; ELISPOT; IFNg release; Negative |
| Envelope Protein | MYSFVSEETGTLIVN | 26954467; MYSFVSEETGTLIVN; Homo sapiens; ELISPOT; IFNg release; Negative |
| Envelope Protein | SVLLFLAFVVFLLVT | 26954467; SVLLFLAFVVFLLVT; Homo sapiens; ELISPOT; IFNg release; Negative |
| Envelope Protein | FLLVTLAILTALRLC | 26954467; FLLVTLAILTALRLC; Homo sapiens; ELISPOT; IFNg release; Negative |
| Envelope Protein | ALRLCAYCCNIVNVS | 26954467; ALRLCAYCCNIVNVS; Homo sapiens; ELISPOT; IFNg release; Negative |
| ORF7a | VFTSCELYHYQECVR | 26954467; VFTSCELYHYQECVR; Homo sapiens; ELISPOT; IFNg release; Negative |
| ORF7a | ELYHYQECVRGTTVL | 26954467; ELYHYQECVRGTTVL; Homo sapiens; ELISPOT; IFNg release; Negative |
| ORF7a | QECVRGTTVLLKEPC | 26954467; QECVRGTTVLLKEPC; Homo sapiens; ELISPOT; IFNg release; Negative |
| ORF7a | PSGTYEGNSPFHPLA | 26954467; PSGTYEGNSPFHPLA; Homo sapiens; ELISPOT; IFNg release; Negative |
| ORF7a | EGNSPFHPLADNKFA | 26954467; EGNSPFHPLADNKFA; Homo sapiens; ELISPOT; IFNg release; Negative |
| ORF7a | FHPLADNKFALTCTS | 26954467; FHPLADNKFALTCTS; Homo sapiens; ELISPOT; IFNg release; Negative |
| ORF7a | SVSPKLFIRQEEVQQ | 26954467; SVSPKLFIRQEEVQQ; Homo sapiens; ELISPOT; IFNg release; Negative |
| ORF7a | LFIRQEEVQQELYSP | 26954467; LFIRQEEVQQELYSP; Homo sapiens; ELISPOT; IFNg release; Negative |
| Membrane Glycoprotein | LEQWNLVIGFLFLAW | 26954467; LEQWNLVIGFLFLAW; Homo sapiens; ELISPOT; IFNg release; Negative |
| Membrane Glycoprotein | YIIKLVFLWLLWPVT | 26954467; YIIKLVFLWLLWPVT; Homo sapiens; ELISPOT; IFNg release; Negative |
| Membrane Glycoprotein | VFLWLLWPVTLACFV | 26954467; VFLWLLWPVTLACFV; Homo sapiens; ELISPOT; IFNg release; Negative |
| Membrane Glycoprotein | LWPVTLACFVLAAVY | 26954467; LWPVTLACFVLAAVY; Homo sapiens; ELISPOT; IFNg release; Negative |
| Membrane Glycoprotein | LACFVLAAVYRINWV | 26954467; LACFVLAAVYRINWV; Homo sapiens; ELISPOT; IFNg release; Negative |
| Membrane Glycoprotein | VASFRLFARTRSMWS | 26954467; VASFRLFARTRSMWS; Homo sapiens; ELISPOT; IFNg release; Negative |
| Membrane Glycoprotein | LFARTRSMWSFNPET | 26954467; LFARTRSMWSFNPET; Homo sapiens; ELISPOT; IFNg release; Negative |
| Membrane Glycoprotein | RSMWSFNPETNILLN | 26954467; RSMWSFNPETNILLN; Homo sapiens; ELISPOT; IFNg release; Negative |
| Membrane Glycoprotein | FNPETNILLNVPLRG | 26954467; FNPETNILLNVPLRG; Homo sapiens; ELISPOT; IFNg release; Negative |
| Membrane Glycoprotein | GRCDIKDLPKEITVA | 26954467; GRCDIKDLPKEITVA; Homo sapiens; ELISPOT; IFNg release; Negative |
| Membrane Glycoprotein | KDLPKEITVATSRTL | 26954467; KDLPKEITVATSRTL; Homo sapiens; ELISPOT; IFNg release; Negative |
| Membrane Glycoprotein | EITVATSRTLSYYKL | 26954467; EITVATSRTLSYYKL; Homo sapiens; ELISPOT; IFNg release; Negative |
| Membrane Glycoprotein | TSRTLSYYKLGASQR | 26954467; TSRTLSYYKLGASQR; Homo sapiens; ELISPOT; IFNg release; Negative |
| Membrane Glycoprotein | SYYKLGASQRVGTDS | 26954467; SYYKLGASQRVGTDS; Homo sapiens; ELISPOT; IFNg release; Negative |
| Membrane Glycoprotein | GFAAYNRYRIGNYKL | 26954467; GFAAYNRYRIGNYKL; Homo sapiens; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | ARPKQRRPQGLPNNT | 16494977; ARPKQRRPQGLPNNT; Macaca cyclopis; ELISA; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | RRPQGLPNNTASWFT | 16494977; RRPQGLPNNTASWFT; Macaca cyclopis; ELISA; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | LSPRWYFYYLGTGPEASL | 16387339; LSPRWYFYYLGTGPEASL; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | NNNAATVLQLPQGTTLPK | 19727132; NNNAATVLQLPQGTTLPK; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | DRLNQLESKVSGKGQQQQ | 19727132; DRLNQLESKVSGKGQQQQ; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | TKKSAAEASKKPRQKRTA | 19727132; TKKSAAEASKKPRQKRTA; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | GRRGPEQTQGNFGDQDLIR | 19727132; GRRGPEQTQGNFGDQDLIR; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | AFFGMSRIGMEVTPSGTW | 19727132; AFFGMSRIGMEVTPSGTW; Mus musculus BALB/c; ELISPOT; IFNg release; Positive-Low |
| Nucleocapsid Phosphoprotein | GMEVTPSGTWLTYHGAIK | 19727132; GMEVTPSGTWLTYHGAIK; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Nucleocapsid Phosphoprotein | PQFKDNVILLNKHIDAYK | 19727132; PQFKDNVILLNKHIDAYK; Mus musculus BALB/c; ELISPOT; IFNg release; Positive-Low |
| Nucleocapsid Phosphoprotein | LLNKHIDAYKTFPPTEPK | 19727132; LLNKHIDAYKTFPPTEPK; Mus musculus BALB/c; ELISPOT; IFNg release; Positive |
| Nucleocapsid Phosphoprotein | YKTFPPTEPKKDKKKK | 19727132; YKTFPPTEPKKDKKKK; Mus musculus BALB/c; ELISPOT; IFNg release; Negative |
| Surface Glycoprotein | SSEVAVLYQDVNCTD | 26954467; SSEVAVLYQDVNCTD; Homo sapiens; ELISPOT; IFNg release; Negative |
| Surface Glycoprotein | YECDIPIGAGICASY | 26954467; YECDIPIGAGICASY; Homo sapiens; ELISPOT; IFNg release; Negative |
| Surface Glycoprotein | SCGSCCKFDEDDSEP | 26954467; SCGSCCKFDEDDSEP; Homo sapiens; ELISPOT; IFNg release; Negative |
| Surface Glycoprotein | CKFDEDDSEPVLKGV | 26954467; CKFDEDDSEPVLKGV; Homo sapiens; ELISPOT; IFNg release; Negative |
| Surface Glycoprotein | DDSEPVLKGVKLHYT | 26954467; DDSEPVLKGVKLHYT; Homo sapiens; ELISPOT; IFNg release; Negative |
|| CoronaVir || India_MOHFW || WHO Advisory || Status || Diagnostics Tests || Genome || Patient Mangagement || Drug Design || Raghava's Group ||
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