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The total number entries retrieved from this search are 6
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Note: Potential Biomarker with * indicates these signatures are candidate biomarkers extracted from experiments on mice, rat or cell lines and they are not validated on human patients'cohort.
Biomarker IDBiomarkerBiomoleculeSubjectRegulationBiomarker's typeExperimentLevel of significanceSourcePMID
2015LDHBProteinHuman Cell linesEmbryonal HB but not fetal HB tissues express LDHB proteins Potential Diagnostic *Embryonal v/s fetal HB (Subtypes of Hepatoblastoma) p < 0.01Tissue28923827
2268LIMK1, CENPE, FZD2, ENO2, ITGA9, COPA, KIAA0660, GTF2H1, VPS41, RGS20, MATK, STOML1, BASP1, EPB42, ALDH3B2, MEL, CAT56, RAB3A, PSCD3, PLD2, ADCYAP1R1, ALDH3B1, RHD, CSF3R, KIAA0063, KIAA0296, LRP6, ENO3, CTRB1, YES1, IncytePD:1404153, GYS1, MDFI, GABRE, IncytePD:2685601, CD3Z, DTYMK, SPTBN2, IncytePRNAsHumanUpregulated in PT than PN (with 3 fold change) DiagnosticMetastatic HCC v/s Primary HCC p < 0.01Tissue12640447
2470HSP27, Enoyl-CoA hydratase, Tubulin β chain, Galactose kinase, Ubiquinol-cytochrome C reductase complex core protein I, Annexin V, P-PST, Ribosome binding protein, Fumarylacetoacetase, ALDH, Catalase,ProteinHumanDifferentially expressed (P-PST, Ribosome binding protein, Fumarylacetoacetase, Catalase and ALDH are Downregulated and rest 6 are Upregulated) in HCC tumor v/s non-tumorous DiagnosticBoth HBV- and HCV associated HCC tumor v/s non-tumorous p < 0.05Tissue14654528
2544SQLE, KIAA1919, ALDH4A1, NKTR, DICER1, C1QB, CYP2A6, EIF1AY, LPA, AKR1C4, GNMT, HLA-DRB4, IGFBP2, GPR88, MBD4, DEFA1, MADH1, HFR4, KIAA1847, FTHFD, SAA1, ASS, CRP, APOF, DBY, ATF5, RPS4Y, SAA2RNAsHumanUpregulated in late cirrhosis than early cirrhosis (with more than 3 fold) PrognosticEarly v/s Late HCV Cirrhosis p < 0.05Tissue15108252
2556VAMP2, ALDH3A2, DPP4, CCL3, HAPLN1, MAN2B1, RBPMS, ACSL6, ITPR2, PLEKHM2, RNF115, CIC, CALR, CENPNRNAsHumanDifferentially expressed gene Prognosticcirrhotic liver tissues with and without hepatocellular carcinoma; can predict prognosis of HCC p < 0.01Tissue19861515
2586APOC1, SEPP1, PDZGEF1, SCML2, ALDH5A1, BNIP3, FBXW1B, PAH, Homo sapiens clone 24473 mRNA sequence, PACE4, FLJ31305 fis or clone LIVER1000104 or , Unknown or , MIG2, RARRES2, BAAT, KDELR2, RNP24, FACL2, KIAA0977 protein, HADHSC, HADHSC, SDHD, CPB2, PGRMC1, AOP2, PPM1A, SDC1, CCL14, ESTRNAsHumanDownregulated in G3 compared with G2 (with Fisher ratio more than 1.3) Prognostic G2 (moderately differentiated) HCV-HCC v/s G2 (poorly differentiated) HCV-HCC; associated with invasion or metastsis P < 0.005Tissue15710396

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