| Detailed information |
|---|
| CancerLivER ID | 2015 |
| Biomarker | LDHB |
| Biomarker Name/Symbol (given in Publication) | LDHB |
| Biomolecule | Protein |
| Subject | Human Cell lines |
| Degree of Validity | Biomarker to distinguish embryonal from fetal components of Hepatoblastoma; but not validated in human subjects |
| Experimental Condition | Embryonal v/s fetal HB (Subtypes of Hepatoblastoma) |
| Cancer type | Hepatoblastoma |
| Regulation | Embryonal HB but not fetal HB tissues express LDHB proteins |
| Level of significance | p < 0.01 |
| Source | Tissue |
| PMID | 28923827 |
| Type of Biomarker | Potential Diagnostic * |
| Pathway | increased Notch versus Wnt path- way activation |
| Cohort | Four HCC (Huh-1,Hep3B, HLE, and HLF) and four HB (Hep-U2, Huh-6, HepG2, and Hep293TT) cell lines |
| Sensitivity | NA |
| Specificity | NA |
| Accuracy | NA |
| AUC | NA |
| Disease | Human Hb (Embryonal) |
| Year of Publication | 2017 |
| Clinical trial | NO |
| Clinical trial (NCT Number) | NA |