Browse result page of B3Pdb

The total number entries retrieved from this search are 318, scroll left/right for detailed information.
B3pdbIDPEPTIDE NAMEPEPTIDE SEQUENCE (1-letter)PEPTIDE SEQUENCE (3-letter)N-TERMINAL MODIFICATIONC-TERMINAL MODIFICATION CHEMICAL MODIFICATIONPEPTIDE LENGTHPEPTIDE CONFORMATIONPEPTIDE NATURESOURCE/ORIGIN OF PEPTIDESMILESCELL LINEIn vitro CONCENTRATIONIn vitro METHODIn vitro RESULTANIMAL MODELIn vivo CONCENTRATIONIn vivo MODE OF DELIVERYIn vivo METHODIn vivo RESULTACTIONTRANSPORT TYPESUBCELLULAR LOCALISATIONCOMBINATIONPHYSICAL CONDITIONRESPONSERESULTLABELPMID
b3pdb_1187AH-DSGSWLRDVWDWICTVLTDFKTWLQSKLSer-Gly-Ser-Trp-Leu-Arg-Asp-Val-Trp-Asp-Trp-Ile-Cys-Thr-Val-Leu-Thr-Asp-Phe-Lys-Thr-Trp-Leu-Gln-Ser-Lys-LeuNANANA27LinearNAChemically synthesizedNANANANANANANAIntravenous NANA NA Permeability NA NA NA Initial disrobution volume 0.0060268 ml/g NA 30349030
b3pdb_1195mouse Des-octanoyl GGSSFLSPEHQKAQQRKESKKPPAKLQPRGly-Ser-Ser-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-ArgNANANA28LinearNAChemically synthesizedNANANANANANANAIntravenous NANA NA Permeability NA NA NA Unidirectional influx rate constant 0.0002606 mL/(g x min) Direct iodination 30293893
b3pdb_1196mouse Des-octanoyl GGSSFLSPEHQKAQQRKESKKPPAKLQPRGly-Ser-Ser-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-ArgNANANA28LinearNAChemically synthesizedNANANANANANANAIntravenous NANA NA Permeability NA NA NA Initial disrobution volume 0.002265 ml/g Direct iodination 30293893
b3pdb_1197ANK6RKRIRLVTKKKRArg-Lys-Arg-Ile-Arg-Leu-Val-Thr-Lys-Lys-Lys-ArgNANANA12LinearNAChemically synthesizedNANANANANANANAIntravenous NANA NA Permeability NA NA NA Peak response 0.3 µL/(g x min) H3/C14 29966196
b3pdb_1198ANK6RKRIRLVTKKKRArg-Lys-Arg-Ile-Arg-Leu-Val-Thr-Lys-Lys-Lys-ArgNANANA12LinearNAChemically synthesizedNANANANANANANAIntravenous NANA NA Permeability NA NA NA Unidirectional influx rate constant 0.0003 mL/(g x min) H3/C14 29966196
b3pdb_1199ANK6RKRIRLVTKKKRArg-Lys-Arg-Ile-Arg-Leu-Val-Thr-Lys-Lys-Lys-ArgNANANA12LinearNAChemically synthesizedNANANANANANANAIntravenous NANA NA Permeability NA NA NA Initial disrobution volume 0.0575 ml/g H3/C14 29966196
b3pdb_1200tANK6RKRIRLVTKKKRRKRIRLVTKKKRArg-Lys-Arg-Ile-Arg-Leu-Val-Thr-Lys-Lys-Lys-Arg-Arg-Lys-Ile-Arg-Leu-Val-Thr-Lys-Lys-Lys-ArgNANANA24LinearNAmouseNANANANANANANAIntravenous NANA NA Permeability NA NA NA Peak response 1.6 µL/(g x min) H3/C14 29966196
b3pdb_1201tANK6RKRIRLVTKKKRRKRIRLVTKKKRArg-Lys-Arg-Ile-Arg-Leu-Val-Thr-Lys-Lys-Lys-Arg-Arg-Lys-Ile-Arg-Leu-Val-Thr-Lys-Lys-Lys-ArgNANANA24LinearNAmouseNANANANANANANAIntravenous NANA NA Permeability NA NA NA Unidirectional influx rate constant 0.0016 mL/(g x min) H3/C14 29966196
b3pdb_1202tANK6RKRIRLVTKKKRRKRIRLVTKKKRArg-Lys-Arg-Ile-Arg-Leu-Val-Thr-Lys-Lys-Lys-Arg-Arg-Lys-Ile-Arg-Leu-Val-Thr-Lys-Lys-Lys-ArgNANANA24LinearNAmouseNANANANANANANAIntravenous NANA NA Permeability NA NA NA Unidirectional influx rate constant 0.5833 ml/g H3/C14 29966196
b3pdb_1203cANK6rRKRIRLVTKKKRRArg-Lys-Arg-Ile-Arg-Leu-Val-Thr-Lys-Lys-Lys-Arg-ArgNANANA13LinearNAChemically synthesizedNANANANANANANAIntravenous NANA NA Permeability NA NA NA Peak response 0.3 µL/(g x min) H3/C14 29966196
b3pdb_1204PEP inhibitory peptiPPLPro-Pro-LeuNANANA3LinearNAChemically synthesizedNANANANANANANAIntravenous NANA NA Permeability NA NA NA Unidirectional influx rate constant 0.0003 mL/(g x min) H3/C14 29966196
b3pdb_1205OP5NFDVLTEQAsn - Phe - Asp - Val - Leu - Thr - Glu - GlnNANANA8LinearNAChemically synthesizedNANANANANANANAIntravenous NANA NA Permeability NA NA NA Unidirectional influx rate constant 0.0396 ml/g H3/C14 29966196
b3pdb_1210PHT-TGN-HBcTGNYKALHPHNGNANANANA12LinearNAChemically synthesizedNAHuman astrocytes HA18000.2 mg PHT/kgConfocal MicroscopyNAMice0.2 mg PHT/kgIntravenous VIS Lumina II Spectrum Imaging SystemIt demonstrated high penetration ability PHT-TGN-HBc NCs showed high antiepileptic effects in epilepsy mouse model with no side effects Permeability Cerebral vasculature Comined with phenytoin and hepatitis B core Refractory Epilepsy It prolongs the circulation time of the drug and efficiently load large amount of drugs, and showed It efficiently target the brain tissue by 2.4 fold and increase the antiepileptic efficiency of phen NA 32087458
b3pdb_1219CGKRK-PEG-DSPECGKRKNANANANA5NANAChemically synthesizedNAU87MG cellsNAFluorescent microscopyIt exhibited enhanced transportationMiceNAIntravenous Fluorescence imaging analysisIt penetrated across the BBB to accumulate at tumor sites with the assistance of Bor and active glio CGKRK-PSNPs combined with borneol could improve the anti-glioma efficacy with the prolonged medium s Transcytosis NA Combined with borneol Glioblastoma NA NA NA 32425792
b3pdb_1222AP9NPNDKYEPFNANAC-terminal amidationNA9LinearNAChemically synthesizedNANANANANAMice20 mg/kgIntravenous Evans blue dyeThe preservation of the protective effect of double AP9 administration in the postischemic period. It induce β-arrestin-2-dependent cytoprotective pathways. NA NA Alone Photothrombosis - induced ischemia NA NA NA 32547356
b3pdb_1223D-penetratinRQIKIWFQNRRMKWKKNANANANA16NANAChemically synthesizedNAIn situ brain perfusion techniqueNACapillary depletion methodVectorization of dox led to a 20-fold increase in the amount of dox transportation.Male Sprague-Dawley rats2.5 mg/kgIntravenous Capillary depletion methodIt led to a significant increase in brain dox concentrations during the first 30 min of postadminist The use of these peptide vectors for brain delivery of dox. Transcytosis Brain parenchyma Combined with Doxorubicin NA NA NA NA 10727512
b3pdb_1224SynB1RGGRLSYSRRRFSTSTGRNANANANA18NANAChemically synthesizedNAIn situ brain perfusion techniqueNACapillary depletion methodVectorization of dox led to a 20-fold increase in the amount of dox transportation.Male Sprague-Dawley rats2.5 mg/kgIntravenous Capillary depletion methodIt led to a significant increase in brain dox concentrations during the first 30 min of postadminist The use of these peptide vectors for brain delivery of dox. Transcytosis Brain parenchyma Combined with Doxorubicin NA NA NA NA 10727512
b3pdb_1225CARTNANANANANANANANANANANANANANAAdult male albino ICR mice2 μgIntravenous HPLCThere is no disruption of the BBB. CART can cross the BBB from blood to brain, but its rapid rate of entry is not inhibited by excess C Diffusion NA NA NA NA NA NA 10567018