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SEFAYGSFVRTVSLPVGADE details |
Primary information | |
---|---|
ID | antitb_1266, |
Name | 24434326 |
N-Terminal modification | F91 |
C-Terminal Modification | SEFAYGSFVRTVSLPVGADE |
Chemical Modification | Free |
Linear/Cyclic | Free |
Length | None |
Chirality | Linear |
Nature | 20 |
Source | L |
Species | Protein Derived |
Strain | From 16kDa antigen |
Inhibition Concentration | None |
In Vitro/ In vivo | None |
Inhibition Concentration | In vivo |
Sequence | 2013 |
Cytotoxicity | NA |
In vivo Model | NA |
Lethal Dose | NA |
Immune Responce | Female BALB/c mice (6-8 wk, 20±2 g) |
Mechanism of Action | 20 nmol |
Target | It promotes the maturation of MHC-II and elicit secretion of IFN-Î¥ and also induce the expression of CD80, CD86 and CD40 co-stimulatory molecules and activate DCs to produce IL-6 and IL-12. |
Combination Therapy | NA |
Other activities | NA |
PMID | None |
Year of Publication | NA |
Tertiary Structure (Technique) | Not Predicted), |
Primary information | |
---|---|
ID | antitb_1267, |
Name | 24434326 |
N-Terminal modification | L91 |
C-Terminal Modification | SEFAYGSFVRTVSLPVGADE |
Chemical Modification | Free |
Linear/Cyclic | Free |
Length | Conjugated to TLR2-ligand Pam2Cys |
Chirality | Linear |
Nature | 20 |
Source | L |
Species | Protein Derived |
Strain | From 16kDa antigen |
Inhibition Concentration | None |
In Vitro/ In vivo | None |
Inhibition Concentration | In vivo |
Sequence | 2013 |
Cytotoxicity | NA |
In vivo Model | NA |
Lethal Dose | NA |
Immune Responce | Female BALB/c mice (6-8 wk, 20±2 g) |
Mechanism of Action | 20 nmol |
Target | It promotes the maturation of MHC-II and elicit secretion of IFN-Î¥ and also induce the expression of CD80, CD86 and CD40 co-stimulatory molecules and activate DCs to produce IL-6 and IL-12. |
Combination Therapy | NA |
Other activities | NA |
PMID | None |
Year of Publication | NA |
Tertiary Structure (Technique) | Not Predicted), |