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Detailed description page of AntiTbPdb

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antitb_1267 details
Primary information
IDantitb_1267
Peptide NameL91
SequenceSEFAYGSFVRTVSLPVGADE
N-terminal ModificationFree
C-terminal ModificationFree
Chemical ModificationConjugated to TLR2-ligand Pam2Cys
Linear/ CyclicLinear
Length20
ChiralityL
NatureNA
SourceProtein Derived
OriginFrom 16kDa antigen
SpeciesNone
StrainNone
Inhibition ConcentartionNA
In vitro/In vivoIn vivo
Cell LineNA
Inhibition ConcentartionNA
CytotoxicityNA
In vivo ModelFemale BALB/c mice (6-8 wk, 20±2 g)
Lethal Dose20 nmol
Immune ResponseIt promotes the maturation of MHC-II and elicit secretion of IFN-Î¥ and also induce the expression of CD80, CD86 and CD40 co-stimulatory molecules and activate DCs to produce IL-6 and IL-12.
Mechanism of ActionNA
TargetNA
Combination TherapyNone
Other ActivitiesNA
Pubmed ID24434326
Year of Publication2013
3-D Structure View in Jmol or Download Structure