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R-(zDhb)-PVLALVAAVAATSAAY details |
| Primary information | |
|---|---|
| ID | antitb_1506, |
| Name | 25681127 |
| N-Terminal modification | SP508A |
| C-Terminal Modification | R-(zDhb)-PVLALVAAVAATSAAY |
| Chemical Modification | R =3-hydroxyldodecanoyl |
| Linear/Cyclic | Free |
| Length | Dhb= Dihydrobutyric acid |
| Chirality | Linear |
| Nature | 18 |
| Source | L |
| Origin | Cationic |
| Species | Natural |
| Strain | Derived from Pseudomonas syringae |
| Inhibition Concentration | Mycobacterium smegmatis |
| In Vitro/ In vivo | Mycobacterium smegmatis ATCC14468 |
| Cell Line | MIC = 31.25 μg/ml |
| Inhibition Concentration | in vitro |
| Sequence | 2015 |
| Cytotoxicity | NA |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | Specific interaction with membrane |
| Other activities | NA |
| PMID | NA |
| Year of Publication | Antibacterial against E.coli, S.aureus, bacillus, pseudomonas |
| Tertiary Structure (Technique) | Not Predicted), |
| Primary information | |
|---|---|
| ID | antitb_1507, |
| Name | 25681127 |
| N-Terminal modification | SP508B |
| C-Terminal Modification | R-(zDhb)-PVLALVAAVAATSAAY |
| Chemical Modification | R =3-hydroxyldodecanoyl |
| Linear/Cyclic | Free |
| Length | Dhb= Dihydrobutyric acid, o-C=o linkage between 12 and 16 amino acid residue |
| Chirality | Cyclic |
| Nature | 18 |
| Source | D |
| Origin | Cationic |
| Species | Natural |
| Strain | Derived from Pseudomonas syringae |
| Inhibition Concentration | Mycobacterium smegmatis |
| In Vitro/ In vivo | Mycobacterium smegmatis ATCC14468 |
| Cell Line | MIC = 62.5 μg/ml |
| Inhibition Concentration | in vitro |
| Sequence | 2015 |
| Cytotoxicity | NA |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | |
| Combination Therapy | Specific interaction with membrane |
| Other activities | NA |
| PMID | NA |
| Year of Publication | Antibacterial against E.coli, S.aureus, bacillus, pseudomonas |
| Tertiary Structure (Technique) | Not Predicted), |
| Primary information | |
|---|---|
| ID | antitb_1510, |
| Name | 25681127 |
| N-Terminal modification | SP508A |
| C-Terminal Modification | R-(zDhb)-PVLALVAAVAATSAAY |
| Chemical Modification | R =3-hydroxyldodecanoyl |
| Linear/Cyclic | Free |
| Length | Dhb= Dihydrobutyric acid |
| Chirality | Linear |
| Nature | 18 |
| Source | L |
| Origin | Cationic |
| Species | Natural |
| Strain | Derived from Pseudomonas syringae |
| Inhibition Concentration | Mycobacterium smegmatis |
| In Vitro/ In vivo | Mycobacterium smegmatis ATCC14468 |
| Cell Line | Reduction in zone to15 mm at 31.25 mg/L |
| Inhibition Concentration | in vitro |
| Sequence | 2015 |
| Cytotoxicity | NA |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | Specific interaction with membrane |
| Other activities | NA |
| PMID | NA |
| Year of Publication | Antibacterial against E.coli, S.aureus, bacillus, pseudomonas |
| Tertiary Structure (Technique) | Not Predicted), |
| Primary information | |
|---|---|
| ID | antitb_1511, |
| Name | 25681127 |
| N-Terminal modification | SP508B |
| C-Terminal Modification | R-(zDhb)-PVLALVAAVAATSAAY |
| Chemical Modification | R =3-hydroxyldodecanoyl |
| Linear/Cyclic | Free |
| Length | Dhb= Dihydrobutyric acid, o-C=o linkage between 12 and 16 amino acid residue |
| Chirality | Cyclic |
| Nature | 18 |
| Source | D |
| Origin | Cationic |
| Species | Natural |
| Strain | Derived from Pseudomonas syringae |
| Inhibition Concentration | Mycobacterium smegmatis |
| In Vitro/ In vivo | Mycobacterium smegmatis ATCC14468 |
| Cell Line | Reduction in zone to 18 mm at 62.5 mg/L |
| Inhibition Concentration | in vitro |
| Sequence | 2015 |
| Cytotoxicity | NA |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Responce | NA |
| Mechanism of Action | NA |
| Target | |
| Combination Therapy | Specific interaction with membrane |
| Other activities | NA |
| PMID | NA |
| Year of Publication | Antibacterial against E.coli, S.aureus, bacillus, pseudomonas |
| Tertiary Structure (Technique) | Not Predicted), |