| Primary information |
|---|
| ID | antitb_1511 |
| Peptide Name | SP508B |
| Sequence | R-(zDhb)-PVLALVAAVAATSAAY |
| N-terminal Modification | R =3-hydroxyldodecanoyl |
| C-terminal Modification | Free |
| Chemical Modification | Dhb= Dihydrobutyric acid, o-C=o linkage between 12 and 16 amino acid residue |
| Linear/ Cyclic | Cyclic |
| Length | 18 |
| Chirality | D |
| Nature | Cationic |
| Source | Natural |
| Origin | Derived from Pseudomonas syringae |
| Species | Mycobacterium smegmatis |
| Strain | Mycobacterium smegmatis ATCC14468 |
| Inhibition Concentartion | Reduction in zone to 18 mm at 62.5 mg/L |
| In vitro/In vivo | in vitro |
| Cell Line | NA |
| Inhibition Concentartion | NA |
| Cytotoxicity | NA |
| In vivo Model | NA |
| Lethal Dose | NA |
| Immune Response | |
| Mechanism of Action | Specific interaction with membrane |
| Target | NA |
| Combination Therapy | NA |
| Other Activities | Antibacterial against E.coli, S.aureus, bacillus, pseudomonas |
| Pubmed ID | 25681127 |
| Year of Publication | 2015 |
| 3-D Structure | NA |