| Primary information |
|---|
| ID | antitb_1883, |
| Name | 28446822 |
| N-Terminal modification | Propeptin |
| C-Terminal Modification | GYPWWDYRDLFGGHTFISP |
| Chemical Modification | Involved in Cyclic bond formation between amino acid 1 and 9 |
| Linear/Cyclic | Free |
| Length | None |
| Chirality | Cyclic |
| Nature | 19 |
| Source | D |
| Species | Natural |
| Strain | Isolated from Microbispora species SNA-115 |
| Inhibition Concentration | Mycobacterium smegmatis |
| In Vitro/ In vivo | Mycobacterium smegmatis M341 |
| Cell Line | MIC90 = 100 μg/mL |
| Inhibition Concentration | In vivo |
| Sequence | 2017 |
| Cytotoxicity | NA |
| In vivo Model | Treatment of infected Mycobacterium smegmatis with 100 μg/ml of Propeptin decreased approximately 90% of the bacterial load |
| Lethal Dose | NA |
| Immune Responce | Silkworm hemolymph infected with mycobacterium smegmatis at (1.25 × 107 CFU) |
| Mechanism of Action | 1.25 × 107 CFU |
| Target | NA |
| Combination Therapy | NA |
| Other activities | NA |
| PMID | None |
| Year of Publication | None |
Tertiary Structure
(Technique) | Not Predicted), |