Primary information |
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ID | antitb_1883 |
Peptide Name | Propeptin |
Sequence | GYPWWDYRDLFGGHTFISP |
N-terminal Modification | Involved in Cyclic bond formation between amino acid 1 and 9 |
C-terminal Modification | Free |
Chemical Modification | None |
Linear/ Cyclic | Cyclic |
Length | 19 |
Chirality | D |
Nature | NA |
Source | Natural |
Origin | Isolated from Microbispora species SNA-115 |
Species | Mycobacterium smegmatis |
Strain | Mycobacterium smegmatis M341 |
Inhibition Concentartion | MIC90 = 100 μg/mL |
In vitro/In vivo | In vivo |
Cell Line | NA |
Inhibition Concentartion | Treatment of infected Mycobacterium smegmatis with 100 μg/ml of Propeptin decreased approximately 90% of the bacterial load |
Cytotoxicity | NA |
In vivo Model | Silkworm hemolymph infected with mycobacterium smegmatis at (1.25 × 107 CFU) |
Lethal Dose | 1.25 × 107 CFU |
Immune Response | NA |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | None |
Other Activities | None |
Pubmed ID | 28446822 |
Year of Publication | 2017 |
3-D Structure | NA |