| Primary information |
|---|
| ID | antitb_1883 |
| Peptide Name | Propeptin |
| Sequence | GYPWWDYRDLFGGHTFISP |
| N-terminal Modification | Involved in Cyclic bond formation between amino acid 1 and 9 |
| C-terminal Modification | Free |
| Chemical Modification | None |
| Linear/ Cyclic | Cyclic |
| Length | 19 |
| Chirality | D |
| Nature | NA |
| Source | Natural |
| Origin | Isolated from Microbispora species SNA-115 |
| Species | Mycobacterium smegmatis |
| Strain | Mycobacterium smegmatis M341 |
| Inhibition Concentartion | MIC90 = 100 μg/mL |
| In vitro/In vivo | In vivo |
| Cell Line | NA |
| Inhibition Concentartion | Treatment of infected Mycobacterium smegmatis with 100 μg/ml of Propeptin decreased approximately 90% of the bacterial load |
| Cytotoxicity | NA |
| In vivo Model | Silkworm hemolymph infected with mycobacterium smegmatis at (1.25 × 107 CFU) |
| Lethal Dose | 1.25 × 107 CFU |
| Immune Response | NA |
| Mechanism of Action | NA |
| Target | NA |
| Combination Therapy | None |
| Other Activities | None |
| Pubmed ID | 28446822 |
| Year of Publication | 2017 |
| 3-D Structure | NA |