Primary information |
---|
ID | antitb_1546, |
Name | 25613372 |
N-Terminal modification | Lassomycin |
C-Terminal Modification | GLRRLFADQLVGRRN |
Chemical Modification | Free |
Linear/Cyclic | Methylation |
Length | Free NH- group of first Glycine form NHCO bond with CO group of eight Asparagine to form cyclic bond |
Chirality | Cyclic |
Nature | 15 |
Source | D |
Origin | Cationic |
Species | Natural |
Strain | Derived from lentzea kentuckyensis |
Inhibition Concentration | Mycobacterium tuberculosis |
In Vitro/ In vivo | Mycobacterium tuberculosis H37Rv |
Cell Line | IC50 = 0.8-3 mg/ml |
Inhibition Concentration | in vitro |
Sequence | 2015 |
Cytotoxicity | NA |
In vivo Model | NA |
Lethal Dose | NA |
Immune Responce | NA |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other activities | NA |
PMID | NA |
Year of Publication | NA |
Tertiary Structure (Technique) | Not Predicted), |
Primary information |
---|
ID | antitb_1547, |
Name | 25613372 |
N-Terminal modification | Lassomycin |
C-Terminal Modification | GLRRLFADQLVGRRN |
Chemical Modification | Free |
Linear/Cyclic | Methylation |
Length | Free NH- group of first Glycine form NHCO bond with CO group of eight Asparagine to form cyclic bond |
Chirality | Cyclic |
Nature | 15 |
Source | D |
Origin | Cationic |
Species | Natural |
Strain | Derived from lentzea kentuckyensis |
Inhibition Concentration | Mycobacterium tuberculosis |
In Vitro/ In vivo | Mycobacterium tuberculosis MDR |
Cell Line | IC50= 0.8-3 mg/ml |
Inhibition Concentration | in vitro |
Sequence | 2015 |
Cytotoxicity | NA |
In vivo Model | NA |
Lethal Dose | NA |
Immune Responce | NA |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other activities | NA |
PMID | NA |
Year of Publication | NA |
Tertiary Structure (Technique) | Not Predicted), |
Primary information |
---|
ID | antitb_1548, |
Name | 25613372 |
N-Terminal modification | Lassomycin |
C-Terminal Modification | GLRRLFADQLVGRRN |
Chemical Modification | Free |
Linear/Cyclic | Methylation |
Length | Free NH- group of first Glycine form NHCO bond with CO group of eight Asparagine to form cyclic bond |
Chirality | Cyclic |
Nature | 15 |
Source | D |
Origin | Cationic |
Species | Natural |
Strain | Derived from lentzea kentuckyensis |
Inhibition Concentration | Mycobacterium tuberculosis |
In Vitro/ In vivo | Mycobacterium tuberculosis XDR |
Cell Line | IC50= 0.8-3 mg/ml |
Inhibition Concentration | in vitro |
Sequence | 2015 |
Cytotoxicity | NA |
In vivo Model | NA |
Lethal Dose | NA |
Immune Responce | NA |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other activities | NA |
PMID | NA |
Year of Publication | NA |
Tertiary Structure (Technique) | Not Predicted), |